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Q2T0N2 (KYNB_BURTA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Kynurenine formamidase

Short name=KFA
EC=3.5.1.9
Alternative name(s):
N-formylkynurenine formamidase
Gene names
Name:kynB
Ordered Locus Names:BTH_I0711
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine By similarity.

Catalytic activity

N-formyl-L-kynurenine + H2O = formate + L-kynurenine.

Pathway

Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.

Sequence similarities

Belongs to the kynB family.

Sequence caution

The sequence ABC37937.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 213213Kynurenine formamidase
PRO_0000362117

Sequences

Sequence LengthMass (Da)Tools
Q2T0N2 [UniParc].

Last modified February 10, 2009. Version 2.
Checksum: B35793CA8DBD3885

FASTA21322,678
        10         20         30         40         50         60 
MDTIWDISPP IAPATPVWPG DTPVGIERVW RIEAGSPVNV ARITLSPHTG AHADAPLHYD 

        70         80         90        100        110        120 
AHGAPIGAVP LDAYLGRCRV IHCIGAHPVV SPDDVRAALA DAPPRVLLRT YGQAPQRAWD 

       130        140        150        160        170        180 
SAFCAVAPQT IDLLAAHGVR LVGIDTPSLD PQESKTMDAH RRIRAHGMAI LEGLVLDEIA 

       190        200        210 
AGDYELIALP LKFATLDASP VRAVLRALPD APR 

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References

[1]"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
BMC Genomics 6:174-174(2005) [PubMed: 16336651] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000086 Genomic DNA. Translation: ABC37937.1. Different initiation.
RefSeqYP_441267.1. NC_007651.1.

3D structure databases

ProteinModelPortalQ2T0N2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2T0N2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3848711.
GenomeReviewsGene locus BTH_I0711 in contig CP000086_GR.
KEGGbte:BTH_I0711.
PATRIC19304204. VBIBurTha36512_3418.
TIGRBTH_I0711.

Phylogenomic databases

eggNOGCOG1878.
HOGENOMHBG686791.
ProtClustDBCLSK930430.

Enzyme and pathway databases

BioCycBTHA271848:BTH_I0711-MONOMER.

Family and domain databases

InterProIPR017484. Arylformamidase.
IPR007325. Cyclase.
[Graphical view]
KOK07130.
PfamPF04199. Cyclase. 1 hit.
[Graphical view]
TIGRFAMsTIGR03035. Trp_arylform. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKYNB_BURTA
AccessionPrimary (citable) accession number: Q2T0N2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 10, 2009
Last modified: January 25, 2012
This is version 32 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families