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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei298UniRule annotation1
Active sitei740UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:BTH_I0871Imported
OrganismiBurkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)Imported
Taxonomic identifieri271848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000001930 Componenti: Chromosome I

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q2T072-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVARASRATA RLAGCASGPH GLRQDPERSF GSRRHPASAS GSGPPPPHRS
60 70 80 90 100
PRRPVSSTDA PARAVQRAPP HRLIALAVAG PQFPFTRAFP RKSIVKSSGS
110 120 130 140 150
ARATRRNAVS SSSAPANAEL PARRAAKTAR KPNGAAARTI APTNAASAKP
160 170 180 190 200
HGRTREDKDR PLFEDIRYLG RLLGDVVREQ EGDAVFDVVE TIRQTAVKFR
210 220 230 240 250
REDDKTAAQT LEKMLRKLTP EQTVSVVRAF SYFSHLANIA EDRHHNRRRR
260 270 280 290 300
IHALAGSAPQ AGTVAYALDK LRQAGDASSK TIKQFFEGAL IVPVLTAHPT
310 320 330 340 350
EVQRKSILDA QHDIARLLAE RDQPLTARER AHNEALLRAR VTTLWQTRML
360 370 380 390 400
RDARLTVADE IENALSYYRA TFLDELPALY TDIEEALAEH GLPARVPAFF
410 420 430 440 450
QMGSWIGGDR DGNPNVTAAT LDEAINRQAA VIFEHYLEQV HKLGAELSVS
460 470 480 490 500
NLLVGASDAL KALAAASPDQ SPHRVDEPYR RALIGVYTRL AASARVRLGE
510 520 530 540 550
GAVPVRSAGR GAAPVRATPY ADAEEFVADL RVLTDSLAVH HGESLATPRL
560 570 580 590 600
APLMRAAEVY GFHLASIDLR QSSDIHEAVI AELLARGGVE PDYAALPEAD
610 620 630 640 650
KLRVLLAALA DPRPLRSPYL DYSDLAKSEL GVLERAHAIR AQFGARAVRN
660 670 680 690 700
YIISHTETVS DLVEVLLLQK ETGLFEGTLG APHANARNGL MVIPLFETIA
710 720 730 740 750
DLRNASDIMR EFFALPGVGE LLAHQGHEQE VMLGYSDSNK DGGFLTSNWE
760 770 780 790 800
LYRAELALVD LFHERGIKLR LFHGRGGTVG RGGGPTYQAI LSQPPGTVNG
810 820 830 840 850
QIRLTEQGEV IASKFANPEI GRRNLETVVA ATLEATLAPH SNAPKQLPAF
860 870 880 890 900
EAAMQTLSDA AMASYRALVY ETPGFTDYFF SSTPITEIAE LNIGSRPASR
910 920 930 940 950
KLQDPKHRKI EDLRAIPWGF SWGQCRLLLT GWYGFGGAVA AYLDGAPDAA
960 970 980 990 1000
ERGKRVALLR KMNKTWPFFA NLLSNMDMVL AKTDLAVASR YAQLVADKKL
1010 1020 1030 1040 1050
RKHVFERIVA EWHRTASALA EITGAQARLA ANPLLARSIK NRFPYLDPLN
1060 1070 1080
HLQVELIKRH RAGDTNARLR RGIHLTINGI AAGLRNTG
Length:1,088
Mass (Da):118,811
Last modified:January 24, 2006 - v1
Checksum:iE1F173592EEA1F07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000086 Genomic DNA Translation: ABC37498.1

Genome annotation databases

EnsemblBacteriaiABC37498; ABC37498; BTH_I0871
KEGGibte:BTH_I0871

Similar proteinsi

Entry informationi

Entry nameiQ2T072_BURTA
AccessioniPrimary (citable) accession number: Q2T072
Entry historyiIntegrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health