ID   Q2T066_BURTA            Unreviewed;       479 AA.
AC   Q2T066;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 103.
DE   SubName: Full=Aldehyde dehydrogenase family protein {ECO:0000313|EMBL:ABC39063.1};
GN   OrderedLocusNames=BTH_I0877 {ECO:0000313|EMBL:ABC39063.1};
OS   Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CCUG 48851 /
OS   CIP 106301 / E264).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848 {ECO:0000313|EMBL:ABC39063.1, ECO:0000313|Proteomes:UP000001930};
RN   [1] {ECO:0000313|EMBL:ABC39063.1, ECO:0000313|Proteomes:UP000001930}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264
RC   {ECO:0000313|Proteomes:UP000001930};
RX   PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA   Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA   DeShazer D.;
RT   "Bacterial genome adaptation to niches: divergence of the potential
RT   virulence genes in three Burkholderia species of different survival
RT   strategies.";
RL   BMC Genomics 6:174-174(2005).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000086; ABC39063.1; -; Genomic_DNA.
DR   RefSeq; WP_009892456.1; NZ_CP008785.1.
DR   AlphaFoldDB; Q2T066; -.
DR   KEGG; bte:BTH_I0877; -.
DR   HOGENOM; CLU_005391_0_2_4; -.
DR   Proteomes; UP000001930; Chromosome I.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd07109; ALDH_AAS00426; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          12..474
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        248
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   479 AA;  50221 MW;  C5043AFF1577BD83 CRC64;
     MEEAKHFIAG AWAPPAGGET IAVIDPSDGE PFARLARGTA PDVDAAVRAA RAAFDGPWGA
     VSAAERGRAL YRLSMLVAAC REELALTESR DTGKPLTQAR ADADALARYF EFYAGAADKL
     HGQTLPYRDG YTVLTLREPH GVTGHIVPWN YPMQILGRSV GAALAAGNAC VVKPSEDACL
     SVLRVATLAA EAGLPAGALN VVTGYGHEAG AALARHPGVD HISFTGSPDT GRLVAQMAAE
     HHAPVTLELG GKSPQIVFAD ADLDAALPVL VSAIVQNAGQ TCSAGSRVLI DKAVYEPLVE
     RLATAFNGLK VGPGQADLDC GPLISAKQQR RVWDFLSDAQ HDGIAMAAHG EVVPDAPETG
     FYQAPALLRD VPHTHRLAQE EVFGPVLAAM KFADEDEALA LANGTPYGLV AGIWTRDGAR
     QMRLARKLRA GQVFVNNYGA GGGVELPFGG TGRSGYGREK GFEALYGFTV LKTIALRHG
//