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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei137 – 1371GTPUniRule annotation
Binding sitei141 – 1411GTPUniRule annotation
Binding sitei185 – 1851GTPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi22 – 265GTPUniRule annotation
Nucleotide bindingi106 – 1083GTPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, SeptationUniRule annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBTHA271848:GJMY-1123-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:BTH_I1123Imported
ORF Names:DR63_1215Imported
OrganismiBurkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)Imported
Taxonomic identifieri271848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000001930 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 203190TubulinInterPro annotationAdd
BLAST
Domaini205 – 323119Tubulin_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiGMAMMGI.
OrthoDBiEOG6S7XZG.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01135. FTSZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2SZH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFEMLETET NGTIIKVIGV GGAGGNAVQH MINKGVQGVD FVVMNTDAQA
60 70 80 90 100
LSRSRAPSVI QLGNTGLGAG AKPEMGRAAA EEARERIADA LRGAHMVFIT
110 120 130 140 150
AGMGGGTGTG AAPVVAQIAK EMGILTVGVV SKPFEFEGGK RMRVAEAGSQ
160 170 180 190 200
QLEDHVDSLI VVLNDKLFEV MGDDAEMDKC FQCADDVLNN AVAGIAEIIN
210 220 230 240 250
VDGLVNVDFE DVKTVMGEQG KAMMGTATVA GVDRARLAAE QAVASPLLEG
260 270 280 290 300
VDLSGARGVL VNITSSRSLR LSETREVMNT IKSYAADDAT VIFGAVYDDA
310 320 330 340 350
MGDALRVTVV ATGLGRAAKK QQSAPMTLLR TGTDNQPISA APQGYAASHH
360 370 380 390
VSTGDYGAFD TPAVWRNSRE TAASHVQALQ EKGVDTYDIP AFLRKQAD
Length:398
Mass (Da):41,600
Last modified:January 24, 2006 - v1
Checksum:i9B48489C2FA99B99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000086 Genomic DNA. Translation: ABC36896.1.
CP008785 Genomic DNA. Translation: AIP25334.1.
RefSeqiWP_004194380.1. NZ_CM000438.1.

Genome annotation databases

EnsemblBacteriaiABC36896; ABC36896; BTH_I1123.
KEGGibte:BTH_I1123.
PATRICi19305138. VBIBurTha36512_3879.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000086 Genomic DNA. Translation: ABC36896.1.
CP008785 Genomic DNA. Translation: AIP25334.1.
RefSeqiWP_004194380.1. NZ_CM000438.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC36896; ABC36896; BTH_I1123.
KEGGibte:BTH_I1123.
PATRICi19305138. VBIBurTha36512_3879.

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiGMAMMGI.
OrthoDBiEOG6S7XZG.

Enzyme and pathway databases

BioCyciBTHA271848:GJMY-1123-MONOMER.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01135. FTSZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
    Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
    BMC Genomics 6:174-174(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E264Imported and E264 / ATCC 700388 / DSM 13276 / CIP 106301Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: E264.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: E264Imported.

Entry informationi

Entry nameiQ2SZH8_BURTA
AccessioniPrimary (citable) accession number: Q2SZH8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: July 6, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.