Q2SYW0 (Q2SYW0_BURTA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lpxc EMBL ABC36485.1

Gene names

Ordered Locus Names:

BTH_I1342

Organism

Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]

Taxonomic identifier

271848 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2SYW0 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: CD4B770A1FF6E37D	FASTA	304	32,760
	10 20 30 40 50 60 MSAPAGWQAR EGTLARELAL SGHGLHTGRR VRVRIAPADG GAHARGIVFR RVWDGRVLAT 70 80 90 100 110 120 LAAGPALRRA QPLCTMLRNE DGVGVRTVEH LLASLLACEI DHAIVELDAE EVPILDGSAL 130 140 150 160 170 180 PWVDALRACG RVALPAPKRF IRVLKPVVVT DGDGAARREM RVEPAARYEL SVRNDLKGFG 190 200 210 220 230 240 DMHWGGVLTP DVFAAEIAPS RSYGRIKWAI PAIVAGYLRG VPILRGARPS CTASIVGSRV 250 260 270 280 290 300 VGGLRQPDEF VRHRVLDLVG DLALAGAPLL GRVSAFRPSH EMNFRLIEAL LSTAGAWEWA EFVA

References

[1]

"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies." Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D. BMC Genomics 6:174-174(2005) [PubMed: 16336651] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000086 Genomic DNA. Translation: ABC36485.1.
RefSeq	YP_441889.1. NC_007651.1.
3D structure databases
ProteinModelPortal	Q2SYW0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2SYW0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3847133.
GenomeReviews	Gene locus BTH_I1342 in contig CP000086_GR.
KEGG	bte:BTH_I1342.
PATRIC	19305606. VBIBurTha36512_4112.
TIGR	BTH_I1342.
Phylogenomic databases
eggNOG	COG0774.
HOGENOM	HBG482342.
OMA	IAFRRVA.
ProtClustDB	PRK13187.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

Q2SYW0_BURTA

Accession

Primary (citable) accession number: Q2SYW0

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)