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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:BTH_I1468
OrganismiBurkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Taxonomic identifieri271848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000001930 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120521 – 282Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST282

Structurei

3D structure databases

ProteinModelPortaliQ2SYI5
SMRiQ2SYI5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q2SYI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNFSSSPPI AFGDLQGCHA AYRQLFAQLS PAADTPLWFA GDLVNRGPAS
60 70 80 90 100
LATLREIVGL GERAVAVLGN HDLHLLAVAA GIRTLKPGDT IGEILDAPDA
110 120 130 140 150
DDLIEWVRHR PFAHFERGML MVHAGLLPQW DAALALELAD ELQRALRAPN
160 170 180 190 200
WRDTLRGLYG NDPNCWSPDL KKADRLRVAF NAFTRIRFCT PEGAMEFRAN
210 220 230 240 250
GGPASAPAGY LPWFDAPSRK TADVTVVFGH WAALGLMLRE NLVALDSGCV
260 270 280
WGNRLSAVRL ADDPAAREVA QVACERCGAA EE
Length:282
Mass (Da):30,602
Last modified:January 24, 2006 - v1
Checksum:iEDFBF07B49C68E59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000086 Genomic DNA Translation: ABC36488.1
RefSeqiWP_009889582.1, NZ_CM000438.1

Genome annotation databases

EnsemblBacteriaiABC36488; ABC36488; BTH_I1468
KEGGibte:BTH_I1468

Similar proteinsi

Entry informationi

Entry nameiAPAH_BURTA
AccessioniPrimary (citable) accession number: Q2SYI5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 24, 2006
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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