Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q2SYE0 (TRMB_BURTA)

Last modified June 16, 2009. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    tRNA (guanine-N(7)-)-methyltransferase
    EC=2.1.1.33
Alternative name(s):
    tRNA(m7G46)-methyltransferase
Gene names
Name: trmB
Ordered Locus Names: BTH_I1513
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.

Catalytic activity

S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N(7)-methylguanine. HAMAP MF_01057

Pathway

tRNA modification; N(7)-methylguanine-tRNA biosynthesis. HAMAP MF_01057

Sequence similarities

Belongs to the methyltransferase superfamily. TrmB family.

Ontologies

Keywords
   Biological processtRNA processing
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtRNA modification

Inferred from electronic annotation. Source: HAMAP

   Molecular functiontRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265tRNA (guanine-N(7)-)-methyltransferase HAMAP MF_01057
PRO_0000288130

Regions

Region241 – 2444Substrate binding Potential

Sites

Binding site951S-adenosyl-L-methionine By similarity
Binding site1201S-adenosyl-L-methionine By similarity
Binding site1471S-adenosyl-L-methionine By similarity
Binding site1701S-adenosyl-L-methionine By similarity
Binding site1741Substrate By similarity
Binding site2061Substrate Potential

Sequences

Sequence LengthMass (Da)Tools
Q2SYE0-1 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 346228F881714D97

FASTA26529,365
        10         20         30         40         50         60 
MNHDDPNASG VPHDDANDAA PASASDAARA TGHADDESSP LHLRRIRSFV TRAGRVSTGQ 

        70         80         90        100        110        120 
RRAIDELGPR FVVPYDNAQP DWDTVFGRRA PRVLEIGFGM GASTAEIAAH RPGDDFIGVE 

       130        140        150        160        170        180 
VHEPGVGALL KLIGEQQLSN IRIIQHDAVE VLEHMIAPDS LDGAHIFFPD PWHKARHHKR 

       190        200        210        220        230        240 
RLIQPPFVAQ LAARLKPGAY LHCATDWQNY AEQMLEVLGA DPSLENTAQD YAPRPDYRPV 

       250        260 
TKFERRGLRL GHGVWDLVFR KKRAG 

« Hide

Cross-references

Sequence databases

CP000086 Genomic DNA. Translation: ABC36287.1.
RefSeqYP_442059.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3846934.
GenomeReviewsGene locus BTH_I1513 in contig CP000086_GR.
KEGGbte:BTH_I1513.
TIGRBTH_I1513.

Phylogenomic databases

HOGENOMQ2SYE0.
OMAQ2SYE0. TKFENRG.

Enzyme and pathway databases

BioCycBTHA271848:BTH_I1513-MON.

Family and domain databases

HAMAPMF_01057.
[Tree]
InterProIPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PANTHERPTHR23417:SF1. Methyltransf_4. 1 hit.
PfamPF02390. Methyltransf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00091. CHP91. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRMB_BURTA
AccessionPrimary (citable) accession number: Q2SYE0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: January 24, 2006
Last modified: June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents