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Reviewed, UniProtKB/Swiss-Prot Q2SYA5 (GLK_BURTA)

Last modified June 16, 2009. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Bifunctional protein glk
Including the following 2 domains:
    1- Recommended name:
            Glucokinase
              EC=2.7.1.2
        Alternative name(s):
            Glucose kinase
    2- Recommended name:
            Putative HTH-type transcriptional regulator
Gene names
Name: glk
Ordered Locus Names: BTH_I1550
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length641 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP MF_00524

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

In the N-terminal section; belongs to the bacterial glucokinase family.

Contains 1 HTH rpiR-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 641641Bifunctional protein glk HAMAP MF_00524
PRO_0000268801

Regions

Transmembrane576 – 59621 Potential
Domain341 – 41777HTH rpiR-type
Nucleotide binding23 – 286ATP Potential
DNA binding377 – 39620H-T-H motif By similarity
Region1 – 340340Glucokinase HAMAP MF_00524
Region341 – 641301Putative HTH-type transcriptional regulator HAMAP MF_00524

Sequences

Sequence LengthMass (Da)Tools
Q2SYA5-1 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 06726A47707F8B7F

FASTA64168,475
        10         20         30         40         50         60 
MSTGAQTKAA EASQHADGPR LLADVGGTNA RFALETGPGE ITQIRVYPGA EYPTLTDAIR 

        70         80         90        100        110        120 
RYLKDVKIGR VNHAAIAIAN PVDGDQVRMT NHNWSFSIEA TRRALGFDTL LVVNDFTALA 

       130        140        150        160        170        180 
MALPGLTDAQ RVQIGAGARR QNSVIGLMGP GTGLGVSGLI PADDRWIALG SEGGHATFAP 

       190        200        210        220        230        240 
MDEREDLVLQ YARRKYPHVS FERVCAGPGM EIIYRALAAR DKKRIAANVV TADIVERAHA 

       250        260        270        280        290        300 
GDALALEAVE CFCGILGTFA GNLAVTLGAL GGIYIGGGVV PKLGELFMRS PFRARFEAKG 

       310        320        330        340        350        360 
RFEAYLANIP TYLITAEYPA FLGVSAILAE QLSNRTGGAS SAVFERIRQM RDALTPAERR 

       370        380        390        400        410        420 
VADLALNHPR SIINDPIVDI ARKADVSQPT VIRFCRSLGC QGLSDFKLKL ATGLTGTIPM 

       430        440        450        460        470        480 
SHSQVHLGDT ATDFGAKVLD NTVSAILQLR EHLNFEHVEQ AIDILNNARR IEFYGLGNSN 

       490        500        510        520        530        540 
IVAQDAHYKF FRFGIPTIAY GDLYMQAASA ALLGKGDVIV AVSKSGRAPE LLRVLDVAMQ 

       550        560        570        580        590        600 
AGAKVIAITS SNTPLAKRAT VALETDHIEM RESQLSMISR ILHLVMIDIL AVGVAIRRAS 

       610        620        630        640 
PNAELAEAMA RAKARAGASA GDEAADVLDW LSHGAAPAAK E 

« Hide

Cross-references

Sequence databases

CP000086 Genomic DNA. Translation: ABC37839.1.
RefSeqYP_442094.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3850093.
GenomeReviewsGene locus BTH_I1550 in contig CP000086_GR.
KEGGbte:BTH_I1550.
TIGRBTH_I1550.

Phylogenomic databases

HOGENOMQ2SYA5.
OMAQ2SYA5. HYLQNIP.

Enzyme and pathway databases

BioCycBTHA271848:BTH_I1550-MON.

Family and domain databases

HAMAPMF_00524. Fused.
[Tree]
InterProIPR003836. Glucokinase.
IPR000843. HTH_LacI.
IPR000281. HTH_RpiR.
IPR001347. SIS.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
PF01418. HTH_6. 1 hit.
PF01380. SIS. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
PROSITEPS00356. HTH_LACI_1. 1 hit.
PS51071. HTH_RPIR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLK_BURTA
AccessionPrimary (citable) accession number: Q2SYA5
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 24, 2006
Last modified: June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents