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Q2SY32 (UBIG_BURTA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-demethylubiquinone-9 3-methyltransferase

EC=2.1.1.64
Alternative name(s):
2-polyprenyl-6-hydroxyphenyl methylase
EC=2.1.1.222
3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase
Short name=DHHB methyltransferase
Gene names
Name:ubiG
Ordered Locus Names:BTH_I1630
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Non-specific O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway By similarity.

Catalytic activity

S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n. HAMAP MF_00472

S-adenosyl-L-methionine + 3-(all-trans-polyprenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-polyprenyl)phenol.

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_00472

Sequence similarities

Belongs to the methyltransferase superfamily. UbiG/COQ3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2322323-demethylubiquinone-9 3-methyltransferase HAMAP MF_00472
PRO_0000241706

Sequences

Sequence LengthMass (Da)Tools
Q2SY32 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 916B7472AE7F3C32

FASTA23225,240
        10         20         30         40         50         60 
MTNADPHELQ KFSDLAHKWW DPNAEFKPLH DLNPIRLNWI DAHAHLPGKR VVDIGCGGGI 

        70         80         90        100        110        120 
LSESMASLGA QVKGIDLATE ALGVADLHSL ESGVSVDYEA IAAEALAARE PGAYDVVTCM 

       130        140        150        160        170        180 
EMLEHVPSPA NIVAACATLV KPGGWVFFST LNRNLKSYLL AVIGAEYIAQ MLPKGTHDYA 

       190        200        210        220        230 
RFIRPSELAH FVRAAGLQLV EIKGITYHPL AKRFALSNDT DVNYLVACRR SV 

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References

[1]"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
BMC Genomics 6:174-174(2005) [PubMed: 16336651] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000086 Genomic DNA. Translation: ABC37743.1.
RefSeqYP_442167.1. NC_007651.1.

3D structure databases

ProteinModelPortalQ2SY32.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2SY32.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3849862.
GenomeReviewsGene locus BTH_I1630 in contig CP000086_GR.
KEGGbte:BTH_I1630.
PATRIC19306226. VBIBurTha36512_4415.
TIGRBTH_I1630.

Phylogenomic databases

eggNOGCOG2227.
HOGENOMHBG738842.
OMADHAEIAK.
ProtClustDBPRK05134.

Enzyme and pathway databases

BioCycBTHA271848:BTH_I1630-MONOMER.

Family and domain databases

HAMAPMF_00472. UbiG.
[Tree]
InterProIPR013216. Methyltransf_11.
IPR010233. UbiG_MeTrfase.
[Graphical view]
KOK00568.
PANTHERPTHR23134. PTHR23134. 1 hit.
PfamPF08241. Methyltransf_11. 1 hit.
[Graphical view]
TIGRFAMsTIGR01983. UbiG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUBIG_BURTA
AccessionPrimary (citable) accession number: Q2SY32
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: January 24, 2006
Last modified: January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families