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Q2SWP6

- G6PI_BURTA

UniProt

Q2SWP6 - G6PI_BURTA

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, BTH_I2132
Organism
Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei350 – 3501Proton donor By similarity
Active sitei381 – 3811 By similarity
Active sitei503 – 5031 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBTHA271848:GJMY-2133-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:BTH_I2132
OrganismiBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
Taxonomic identifieri271848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
ProteomesiUP000001930: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 540540Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000252612Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi271848.BTH_I2132.

Structurei

3D structure databases

ProteinModelPortaliQ2SWP6.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2SWP6-1 [UniParc]FASTAAdd to Basket

« Hide

MTLNSLPVWP ALQAHYEEIR DAHLRDWFAP ANDRAPTRAE RFTFEGGGLA    50
ADFSKNLITD ATLALLVRLA REAGVEARRD AMFAGETVNP TEGRAALHTA 100
LRANSPDAPF HAQVAAERAK MARFADAVRA GAWTGYTGKR IRHVVNIGIG 150
GSDLGPKMVV HALHHVATPD IATHFVSNVD GADLARVLER IDPQETLAII 200
VSKTFTTLET MTNARSLREW FVANGCPEDA LAKHFVGVSA NPAEVVKFGI 250
AEANVFEMWD WVGGRYSLWS AVGLSIMIAI GPERFAELLA GAHDMDEHFR 300
TAPLERNLPV LQGLVGIWYR NFFGAQSYLV APYSEALHYL PSYLQQLEME 350
SNGKSAQIDG AFVDYPTSAV TWGEPGTNGQ HAFFQMLHQG PTLVPIDFIA 400
VLTPEHPLAS HHPKLLANCF AQSEALMLGR TLDEARKIAG PAHPELAPHL 450
TFPGNRPTTT LLVDALTPRT LGALIALYEH KVLVQAAVWN INPFDQWGVE 500
LGKILGKVVE ADLTAPQVDP AKHDSSTSAL IARARKALGE 540
Length:540
Mass (Da):58,824
Last modified:October 17, 2006 - v2
Checksum:i0B714711F2C5CD05
GO

Sequence cautioni

The sequence ABC38603.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000086 Genomic DNA. Translation: ABC38603.1. Different initiation.
RefSeqiYP_442653.1. NC_007651.1.

Genome annotation databases

EnsemblBacteriaiABC38603; ABC38603; BTH_I2132.
GeneIDi3847875.
KEGGibte:BTH_I2132.
PATRICi19307314. VBIBurTha36512_4943.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000086 Genomic DNA. Translation: ABC38603.1 . Different initiation.
RefSeqi YP_442653.1. NC_007651.1.

3D structure databases

ProteinModelPortali Q2SWP6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 271848.BTH_I2132.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC38603 ; ABC38603 ; BTH_I2132 .
GeneIDi 3847875.
KEGGi bte:BTH_I2132.
PATRICi 19307314. VBIBurTha36512_4943.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci BTHA271848:GJMY-2133-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
    Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
    BMC Genomics 6:174-174(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Entry informationi

Entry nameiG6PI_BURTA
AccessioniPrimary (citable) accession number: Q2SWP6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: October 17, 2006
Last modified: June 11, 2014
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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