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Q2SWF5 (SURE_BURTA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
5'-nucleotidase surE

EC=3.1.3.5
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase
Gene names
Name:surE
Ordered Locus Names:BTH_I2223
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060

Catalytic activity

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060

Cofactor

Binds 1 divalent metal cation per subunit By similarity.

Subcellular location

Cytoplasm Potential HAMAP MF_00060.

Sequence similarities

Belongs to the surE nucleotidase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMetal-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function5'-nucleotidase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

nucleotide binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2532535'-nucleotidase surE HAMAP MF_00060
PRO_0000235602

Sites

Metal binding81Divalent metal cation By similarity
Metal binding91Divalent metal cation By similarity
Metal binding391Divalent metal cation By similarity
Metal binding921Divalent metal cation By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2SWF5 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: E1CA72B1F49C84ED

FASTA25326,980
        10         20         30         40         50         60 
MRILLSNDDG YLAPGLAALY EALRPLAEVM VMAPEQNCSG ASNSLTLSRP LSVSRSATTG 

        70         80         90        100        110        120 
FYYVNGTPTD SVHVALTGML DAKPDLVVSG INNGQNMGDD TLYSGTVAAA TEGIMFGVPA 

       130        140        150        160        170        180 
IAFSLVHKEW AHLEDAARVA AEIVRHYLDH PLPGQPLLNV NIPNLPYGEL RGWRVTRLGK 

       190        200        210        220        230        240 
RHPSQPVIRQ INPRGEPIYW IGAAGDALDA SEGTDFHATA AGYVSITPLQ LDLTHTQMLA 

       250 
ATRDWAHAGS GAS 

« Hide

References

[1]"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
BMC Genomics 6:174-174(2005) [PubMed: 16336651] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000086 Genomic DNA. Translation: ABC37753.1.
RefSeqYP_442744.1. NC_007651.1.

3D structure databases

ProteinModelPortalQ2SWF5.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2SWF5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3847622.
GenomeReviewsGene locus BTH_I2223 in contig CP000086_GR.
KEGGbte:BTH_I2223.
PATRIC19307514. VBIBurTha36512_5043.
TIGRBTH_I2223.

Phylogenomic databases

eggNOGCOG0496.
HOGENOMHBG600532.
OMANGFYYVN.
ProtClustDBPRK00346.

Enzyme and pathway databases

BioCycBTHA271848:BTH_I2223-MONOMER.

Family and domain databases

HAMAPMF_00060. SurE.
[Tree]
InterProIPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
Gene3DG3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KOK03787.
PfamPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMSSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMsTIGR00087. SurE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSURE_BURTA
AccessionPrimary (citable) accession number: Q2SWF5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: January 24, 2006
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families