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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi13 – 186FADUniRule annotation
Nucleotide bindingi274 – 28815NADUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein, NAD

Enzyme and pathway databases

BioCyciBTHA271848:GJMY-3320-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:BTH_I3320
OrganismiBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
Taxonomic identifieri271848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000001930 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 657657tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGPRO_1000016570Add
BLAST

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ2STD7.
SMRiQ2STD7. Positions 1-562.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000201060.
KOiK03495.
OMAiFRPGYAI.
OrthoDBiEOG6W9X6J.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2STD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYPIEFDVI VVGGGHAGTE AALASARMGA KTLLLTHNIE TLGQMSCNPS
60 70 80 90 100
IGGIGKGHLV KEVDALGGAM AAATDEGGIQ FRILNSSKGP AVRATRAQAD
110 120 130 140 150
RVLYKQAIRR YLENQPNLWL FQQAVDDLMV EGDRVVGAVT QVGVRFRARA
160 170 180 190 200
VVLTAGTFLD GKIHVGLNNY TGGRAGDPAA VSLSSRLKEL KLPQGRLKTG
210 220 230 240 250
TPPRIDGRTI DFSKLEEQPG DLDPVPVFSF LGRPEQHPEQ LPCWVTHTNE
260 270 280 290 300
RTHDIIRSGL DRSPMYTGVI EGVGPRYCPS IEDKIHRFAS KDSHQIFLEP
310 320 330 340 350
EGLTTNEFYP NGISTSLPFD VQLALVHSMR GLEQAHILRP GYAIEYDYFD
360 370 380 390 400
PRALKSSLET KAINGLFFAG QINGTTGYEE AAAQGLLAGI NAGRHALEKE
410 420 430 440 450
AWCPRRDQAY LGVLVDDLVT RGVSEPYRMF TSRAEYRLSL REDNADMRLT
460 470 480 490 500
EIGRELGVVD DVRWDAFNRK RDAVSRETER LRTTWVTPKT LPADEATELL
510 520 530 540 550
GKPIDHEYSL AELLRRPGIS YDGVCGLRGG ECGPSEPLAE DALLLAQIKE
560 570 580 590 600
QIEIGIKYQG YIERQAGEIE RNGANENTRL PDGIDYTEVR GLSFEVSQKL
610 620 630 640 650
NQFRPETIGQ ASRISGVTPA AISLLMVHLK KRGLGRRKGA DSAPGADAET

NSAATQQ
Length:657
Mass (Da):71,977
Last modified:January 24, 2006 - v1
Checksum:i2353750E1F8BE42A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000086 Genomic DNA. Translation: ABC37141.1.
RefSeqiWP_009910302.1. NC_007651.1.

Genome annotation databases

EnsemblBacteriaiABC37141; ABC37141; BTH_I3320.
KEGGibte:BTH_I3320.
PATRICi19309894. VBIBurTha36512_6207.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000086 Genomic DNA. Translation: ABC37141.1.
RefSeqiWP_009910302.1. NC_007651.1.

3D structure databases

ProteinModelPortaliQ2STD7.
SMRiQ2STD7. Positions 1-562.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC37141; ABC37141; BTH_I3320.
KEGGibte:BTH_I3320.
PATRICi19309894. VBIBurTha36512_6207.

Phylogenomic databases

HOGENOMiHOG000201060.
KOiK03495.
OMAiFRPGYAI.
OrthoDBiEOG6W9X6J.

Enzyme and pathway databases

BioCyciBTHA271848:GJMY-3320-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
    Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
    BMC Genomics 6:174-174(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Entry informationi

Entry nameiMNMG_BURTA
AccessioniPrimary (citable) accession number: Q2STD7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 24, 2006
Last modified: January 20, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.