Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q2SSA3 (SYR_MYCCT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:MCAP_0376
OrganismMycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154) [Complete proteome] [HAMAP]
Taxonomic identifier340047 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length554 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 554554Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242046

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q2SSA3 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: DCB6C2770006D705

FASTA55463,494
        10         20         30         40         50         60 
MNRTIIEMFY DDLKNICQKF NITKEPIIEI NKNNTPGLLS SSICLISSKQ VNKKPLDLAN 

        70         80         90        100        110        120 
DFKEQLLLTN NYSSIQIANP GFLNVLVKPE ILSNVISNVL TLKSKYGNLE KQNKIINIEY 

       130        140        150        160        170        180 
VSANPTGYLH VGHARNAVIG SVLVNLFKKA GYKVQTEYYV NDAGNQINVL AVTVFVHYLQ 

       190        200        210        220        230        240 
ALNIDAKKPE NCYAGEMYDD LAKIIINKYN DQFKDIKYTD NKILDDNVHS LFKQISIDYF 

       250        260        270        280        290        300 
LKIIKQQLAD FNVKIRHWSS EQEVYDTHQI EKVLKLYKSK DASYYKDGAE FLKTTQFGDD 

       310        320        330        340        350        360 
KDRVLVKSDK TYTYILPDLA THHLRIKRTK ADKLINVWGG DHHGYIKRMQ AGLALLGNDP 

       370        380        390        400        410        420 
DILEIQMVQM VRLIKDGSEY KMSKRKGTAV WLVDILELVG VDALRYMLAS KSSNSHMDLD 

       430        440        450        460        470        480 
LDLITLKNSS NPIYYAQYAT ARCHSILNQA KIKKITPLVK ETNLLNNPKE IELLLILDNF 

       490        500        510        520        530        540 
KEVIKNSANN RSTQQICDYI QNICKIFHSY YAEIKIIDEN NLELTKLRLG FIKAILQVLK 

       550 
NAFFIIGIQP VVEM 

« Hide

References

[1]Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O., Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: California kid / ATCC 27343 / NCTC 10154.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000123 Genomic DNA. Translation: ABC01557.1.
RefSeqYP_424360.1. NC_007633.1.

3D structure databases

ProteinModelPortalQ2SSA3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING340047.MCAP_0376.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC01557; ABC01557; MCAP_0376.
GeneID3828392.
KEGGmcp:MCAP_0376.
PATRIC20005225. VBIMycCap130493_0381.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycMCAP340047:GC0H-374-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_MYCCT
AccessionPrimary (citable) accession number: Q2SSA3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: January 24, 2006
Last modified: April 16, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries