Q2SS69 (NANE_MYCCT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative N-acetylmannosamine-6-phosphate 2-epimerase
EC=5.1.3.9

Alternative name(s):
ManNAc-6-P epimerase

Gene names

Name:	nanE
Ordered Locus Names:	MCAP_0419

Organism

Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154) [Complete proteome] [HAMAP]

Taxonomic identifier

340047 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	226 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) Potential. HAMAP MF_01235
Catalytic activity	N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate. HAMAP MF_01235
Pathway	Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 3/5. HAMAP MF_01235
Sequence similarities	Belongs to the nanE family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	N-acetylmannosamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	N-acylglucosamine-6-phosphate 2-epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 226	226	Putative N-acetylmannosamine-6-phosphate 2-epimerase HAMAP MF_01235		PRO_0000301478

Sequences

	Sequence		Length	Mass (Da)
	Q2SS69 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 8110A0BF2584EAA3	FASTA	226	25,135
	10 20 30 40 50 60 MDLINQIKNT LIVSCQAIGD EPLNDSYVLS KMAYALVLGG SKVLRLSQVE HIKAVKQVVD 70 80 90 100 110 120 VPIIGLIKKH YDNSEVFITP TIKEVDQLVD LKVDIIALDA TLRTRPDQDL TNLVKTIKTK 130 140 150 160 170 180 YPNQLLLADC SSVEDAINAQ NLGFDLIAST LRGSTKQTKG HNNLENNYQF LRDLKKVITK 190 200 210 220 PIIAEGGIWT PQQAKEILNL GIHSVVVGTA ITRLHSIVKY WNDILK

References

[1]

Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O., Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: California kid / ATCC 27343 / NCTC 10154.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000123 Genomic DNA. Translation: ABC01577.1.
RefSeq	YP_424394.1. NC_007633.1.
3D structure databases
HSSP	HSSP built from PDB template 1YXY based on UniProtKB P65522.
ProteinModelPortal	Q2SS69.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2SS69.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3828617.
GenomeReviews	Gene locus MCAP_0419 in contig CP000123_GR.
KEGG	mcp:MCAP_0419.
PATRIC	20005309. VBIMycCap130493_0415.
TIGR	MCAP_0419.
Phylogenomic databases
eggNOG	COG3010.
HOGENOM	HBG296941.
OMA	CQALEDE.
PhylomeDB	Q2SS69.
ProtClustDB	PRK01130.
Enzyme and pathway databases
BioCyc	MCAP340047:MCAP_0419-MONOMER.
Family and domain databases
HAMAP	MF_01235. ManNAc6P_epimer. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR007260. NanE. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01788.
Pfam	PF04131. NanE. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NANE_MYCCT

Accession

Primary (citable) accession number: Q2SS69

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	January 24, 2006
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program