Reviewed, UniProtKB/Swiss-Prot Q2SS69 (NANE_MYCCT)

Names and origin

Protein names

Recommended name:
    Putative N-acetylmannosamine-6-phosphate 2-epimerase
    EC=5.1.3.9
Alternative name(s):
    ManNAc-6-P epimerase

Gene names

Name:	nanE
Ordered Locus Names:	MCAP_0419

Organism

Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154) [Complete proteome] [HAMAP]

Taxonomic identifier

340047 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	226 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) Potential.
Catalytic activity	N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate. HAMAP MF_01235
Pathway	Amino-sugar metabolism; N-acetylneuraminic acid degradation; D-fructose 6-phosphate from N-acetylneuraminic acid: step 3/5. HAMAP MF_01235
Sequence similarities	Belongs to the nanE family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	N-acetylmannosamine metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	N-acylglucosamine-6-phosphate 2-epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 226	226	Putative N-acetylmannosamine-6-phosphate 2-epimerase HAMAP MF_01235		PRO_0000301478

Sequences

	Sequence		Length	Mass (Da)
	Q2SS69-1 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 8110A0BF2584EAA3	FASTA	226	25,135
	10 20 30 40 50 60 MDLINQIKNT LIVSCQAIGD EPLNDSYVLS KMAYALVLGG SKVLRLSQVE HIKAVKQVVD 70 80 90 100 110 120 VPIIGLIKKH YDNSEVFITP TIKEVDQLVD LKVDIIALDA TLRTRPDQDL TNLVKTIKTK 130 140 150 160 170 180 YPNQLLLADC SSVEDAINAQ NLGFDLIAST LRGSTKQTKG HNNLENNYQF LRDLKKVITK 190 200 210 220 PIIAEGGIWT PQQAKEILNL GIHSVVVGTA ITRLHSIVKY WNDILK

References

[1]	Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O., Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000123 Genomic DNA. Translation: ABC01577.1.
RefSeq	YP_424394.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3828617.
GenomeReviews	Gene locus MCAP_0419 in contig CP000123_GR.
KEGG	mcp:MCAP_0419.
TIGR	MCAP_0419.
Phylogenomic databases
HOGENOM	Q2SS69.
OMA	Q2SS69. YNTPELA.
Enzyme and pathway databases
BioCyc	MCAP340047:MCAP_0419-MON.
Family and domain databases
HAMAP	MF_01235. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR007260. NanE. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF04131. NanE. 1 hit. [Graphical view]
ProDom	PD149806. TMP_synthase. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

NANE_MYCCT

Accession

Primary (citable) accession number: Q2SS69

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	January 24, 2006
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)