Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q2SS24 (G6PI_MYCCT) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:MCAP_0465
OrganismMycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154) [Complete proteome] [HAMAP]
Taxonomic identifier340047 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma ›

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP-Rule MF_00473

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000230920

Sites

Active site2771Proton donor By similarity
Active site2981 By similarity
Active site4141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2SS24 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: D1CAE9A23AF8BCA0

FASTA42748,526
        10         20         30         40         50         60 
MIKVNLDHTD ININKVADLN KIKEIHQMIF NKTGKGNDFL GWLNWPVNFN KTEYEQMKLV 

        70         80         90        100        110        120 
ANDLKNQIEV LVVIGIGGSY LGCRAADEMI RGLYHQNKVE LIYTGNTMSS TYIYQVVEYL 

       130        140        150        160        170        180 
KNKNFGICVI SKSGTTTEPG ISFRVFEKLL VDKVGLEKAK SLIVAITDKN KGALKQLAEK 

       190        200        210        220        230        240 
KGYQTFVIPN DIGGRFSVLT PVGIFPLLVS GINTDKIFQG ALKAKNDLIN DDLSNQAYKY 

       250        260        270        280        290        300 
AVVRNYLYNQ GYKTEALISY ELQLQMLTEW WKQLFGESEG KENKGLLPSS MIFSTDLHSL 

       310        320        330        340        350        360 
GQWVQEGPRN VMFETIIKIE KPNHDLNVPI DEDNYDGLNY LTKKSFHQIN QTALKGVIQA 

       370        380        390        400        410        420 
HSVTGKMPNI VLEFEKMDDE QFGYLVYFFE LALAMSAYLL DVNPFNQPGV EVYKYNMFKL 


LNKPGIK

« Hide

References

[1]Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O., Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: California kid / ATCC 27343 / NCTC 10154.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000123 Genomic DNA. Translation: ABC01694.1.
RefSeqYP_424439.1. NC_007633.1.

3D structure databases

ProteinModelPortalQ2SS24.
ModBaseSearch...

Protein-protein interaction databases

STRING340047.MCAP_0465.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC01694; ABC01694; MCAP_0465.
GeneID3828818.
KEGGmcp:MCAP_0465.
PATRIC20005401. VBIMycCap130493_0461.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100403.
KOK01810.
OMAEPSLHFV.
OrthoDBEOG64R61J.
ProtClustDBPRK14097.

Enzyme and pathway databases

BioCycMCAP340047:GC0H-462-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_MYCCT
AccessionPrimary (citable) accession number: Q2SS24
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: January 24, 2006
Last modified: November 13, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents