ID   ADD_HAHCH               Reviewed;         334 AA.
AC   Q2SLW3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Adenosine deaminase;
DE            EC=3.5.4.4;
DE   AltName: Full=Adenosine aminohydrolase;
GN   Name=add; OrderedLocusNames=HCH_01503;
OS   Hahella chejuensis (strain KCTC 2396).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Hahellaceae; Hahella.
OX   NCBI_TaxID=349521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16352867; DOI=10.1093/nar/gki1016;
RA   Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H.,
RA   Hur C.-G., Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H.,
RA   Park H.-S., Lee H.K., Oh T.K., Kim J.F.;
RT   "Genomic blueprint of Hahella chejuensis, a marine microbe producing
RT   an algicidal agent.";
RL   Nucleic Acids Res. 33:7066-7073(2005).
CC   -!- CATALYTIC ACTIVITY: Adenosine + H(2)O = inosine + NH(3).
CC   -!- SIMILARITY: Belongs to the adenosine and AMP deaminases family.
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DR   EMBL; CP000155; ABC28361.1; -; Genomic_DNA.
DR   RefSeq; YP_432786.1; -.
DR   GeneID; 3838829; -.
DR   GenomeReviews; CP000155_GR; HCH_01503.
DR   KEGG; hch:HCH_01503; -.
DR   NMPDR; fig|349521.5.peg.1353; -.
DR   HOGENOM; Q2SLW3; -.
DR   OMA; Q2SLW3; LAQNSLD.
DR   BioCyc; HCHE349521:HCH_01503-MON; -.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:HAMAP.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynt...; IEA:HAMAP.
DR   HAMAP; MF_00540; -; 1.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR001365; A/AMP_deaminase.
DR   InterPro; IPR006330; A_deaminase.
DR   PANTHER; PTHR11409; A/AMP_deaminase; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   TIGRFAMs; TIGR01430; aden_deam; 1.
DR   PROSITE; PS00485; A_DEAMINASE; FALSE_NEG.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Nucleotide metabolism.
FT   CHAIN         1    334       Adenosine deaminase.
FT                                /FTId=PRO_1000017663.
FT   ACT_SITE    194    194       Potential.
FT   ACT_SITE    242    242       Potential.
FT   ACT_SITE    275    275       Potential.
FT   ACT_SITE    276    276       Potential.
SQ   SEQUENCE   334 AA;  38111 MW;  C4379DD26145913A CRC64;
     MQDFLKGLPK AELHLHIEGS LEPELMFEIG RRNGVALPFA NVEEVRAAYE FNNLQEFLDI
     YYQGAQVLLH EQDFYDMTFA YLQRCREQNV IHAEMFFDPQ THTDRGVDIG VVIRGLTRAM
     EDAEIQWGQS SKLILCFLRH LSEDAAIETL RQALPYKQHF VGVGLDSSEV GHPPEKFQRV
     FEQAQNAGLL TVAHAGEEGP PEYIWQALDL LKVKRIDHGV RCIEDAALMQ RLIDEQIPLT
     VCPLSNIKLC VFDSMSEHNI LRLLEKGLKV TVNSDDPAYF GGYMNENFIA MQEALPMSKE
     QAAQLARNSF EASFLTSEEK ARLLARLDQY LQNH
//