Q2SLV0 (TYPH_HAHCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative thymidine phosphorylase
EC=2.4.2.4

Alternative name(s):
TdRPase

Gene names

Ordered Locus Names:

HCH_01516

Organism

Hahella chejuensis (strain KCTC 2396) [Complete proteome] [HAMAP]

Taxonomic identifier

349521 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Hahellaceae › Hahella › Hahella chejuensis

Protein attributes

Sequence length	505 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703
Sequence similarities	Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pyrimidine nucleobase metabolic process Inferred from electronic annotation. Source: InterPro pyrimidine nucleoside metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	phosphorylase activity Inferred from electronic annotation. Source: InterPro thymidine phosphorylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 505	505	Putative thymidine phosphorylase HAMAP-Rule MF_00703		PRO_0000314699

Sequences

	Sequence		Length	Mass (Da)
	Q2SLV0 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: A7F6F18E58002A9E	FASTA	505	54,055
	10 20 30 40 50 60 MQQRELNYLF LKRIGINTHQ EPVVYMRQDC HVCRSEGFNA HSRVRVTTNK RSIIATVHQV 70 80 90 100 110 120 TDGWLSHQEA GLSDAAWRLL EAEDGEVAYF SHTKAVDSMS HVRGKLYGAS LTQESADEVV 130 140 150 160 170 180 KDVAGGLYSD VQLAAFVTAC AGSRLNQDEV AALTSAMVKV GQRIDWGTSP IMDKHCVGGL 190 200 210 220 230 240 PGNRTTPIVV AIVTACGLRM PKTSSRAITS PAGTADTMET MAPVNLTLAQ MKKVVEQEGG 250 260 270 280 290 300 CIAWGGSVSL SPADDVLIRI ERALDLDSEG QLVASVISKK VAAGSTHVLI DIPIGMTAKV 310 320 330 340 350 360 RSPEYAERLA SHMRYTGVKL GIQVEAMFTD GAQPVGRGIG PALEARDILA VLRNQAEAPA 370 380 390 400 410 420 DLRVRALTLA GRLLEIGGVA SHGAGVARAR ETLESGAALH KFMAICEAQG GFREPALAPH 430 440 450 460 470 480 CYEATADRVG VVSFVNNRFV AKLAKLAGAP SNSSAGVDFH VKLGQKVRVG EPLFSIYAEA 490 500 PGELAYALDF LRDHPNEIRI EEESL

References

[1]

"Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent." Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G., Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K., Oh T.K., Kim J.F. Nucleic Acids Res. 33:7066-7073(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KCTC 2396.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000155 Genomic DNA. Translation: ABC28374.1.
RefSeq	YP_432799.1. NC_007645.1.
3D structure databases
ProteinModelPortal	Q2SLV0.
ModBase	Search...
Protein-protein interaction databases
STRING	349521.HCH_01516.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3838842.
KEGG	hch:HCH_01516.
PATRIC	22083994. VBIHahChe29232_1403.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0213.
HOGENOM	HOG000252767.
KO	K00758.
OMA	VHSIGGV.
ProtClustDB	PRK04350.
Enzyme and pathway databases
BioCyc	HCHE349521:GHAL-1536-MONOMER.
Family and domain databases
Gene3D	3.40.1030.10. 1 hit. 3.90.1170.30. 1 hit.
HAMAP	MF_00703. Thymid_phosp_2.
InterPro	IPR000312. Glycosyl_Trfase_fam3. IPR017459. Glycosyl_Trfase_fam3_N_dom. IPR013102. PYNP_C. IPR000053. Pyrmidine_PPase. IPR017872. Pyrmidine_PPase_CS. IPR013466. Thymidine_Pase_type2. [Graphical view]
PANTHER	PTHR10515. PTHR10515. 1 hit.
Pfam	PF02885. Glycos_trans_3N. 1 hit. PF00591. Glycos_transf_3. 1 hit. PF07831. PYNP_C. 1 hit. [Graphical view]
PIRSF	PIRSF000478. TP_PyNP. 1 hit.
SMART	SM00941. PYNP_C. 1 hit. [Graphical view]
SUPFAM	SSF47648. Glyco_trans_3. 1 hit. SSF52418. Glyco_trans_3. 1 hit. SSF54680. PYNP_C. 1 hit.
TIGRFAMs	TIGR02645. ARCH_P_rylase. 1 hit.
PROSITE	PS00647. THYMID_PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TYPH_HAHCH

Accession

Primary (citable) accession number: Q2SLV0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 24, 2006
Last modified:	May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program