Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2SLC0

- GCH4_HAHCH

UniProt

Q2SLC0 - GCH4_HAHCH

Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Hahella chejuensis (strain KCTC 2396)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (24 Jan 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotation

    Catalytic activityi

    GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei156 – 1561May be catalytically importantUniRule annotation

    GO - Molecular functioni

    1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciHCHE349521:GHAL-1641-MONOMER.
    UniPathwayiUPA00848; UER00151.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
    Gene namesi
    Name:folE2UniRule annotation
    Ordered Locus Names:HCH_01706
    OrganismiHahella chejuensis (strain KCTC 2396)
    Taxonomic identifieri349521 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHahellaceaeHahella
    ProteomesiUP000000238: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 304304GTP cyclohydrolase FolE2PRO_0000289492Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi349521.HCH_01706.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2SLC0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP cyclohydrolase IV family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1469.
    HOGENOMiHOG000247517.
    KOiK09007.
    OMAiAGRTTIQ.
    OrthoDBiEOG6X6RBH.

    Family and domain databases

    HAMAPiMF_01527_B. GTP_cyclohydrol_B.
    InterProiIPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view]
    PfamiPF02649. GCHY-1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2SLC0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQIVRALPDI AKTRTEFETY TLQWVGMEDI AVPLTLNIGG GKQQSLPAKA    50
    NVYVSLDDAA EKGIHMSRLH AILNQLASQV CDKEGLDLLL RNMVASQGKI 100
    SRSAKVELVF DLLLPKPSLL SNETGFQTYR IEIGGQCLSE KYDYSLKITV 150
    PYSSTCPCSA ALSRQLFSDA IDNEFSTSRI DKQELLSWAL TSTVATPHSQ 200
    RSYAYLNLLL GNHGWPSLSS FIMQIEEAIG TPVQTMVKRT DEQEFARLNA 250
    DNLMFCEDAA RNVKTLLEQS SWIEDYWFKV EHQESLHAHN AVVIDQKYSK 300
    GAML 304
    Length:304
    Mass (Da):34,042
    Last modified:January 24, 2006 - v1
    Checksum:i57CE0983D7FB7CBD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000155 Genomic DNA. Translation: ABC28554.1.
    RefSeqiWP_011395626.1. NC_007645.1.
    YP_432979.1. NC_007645.1.

    Genome annotation databases

    EnsemblBacteriaiABC28554; ABC28554; HCH_01706.
    GeneIDi3839058.
    KEGGihch:HCH_01706.
    PATRICi22084352. VBIHahChe29232_1574.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000155 Genomic DNA. Translation: ABC28554.1 .
    RefSeqi WP_011395626.1. NC_007645.1.
    YP_432979.1. NC_007645.1.

    3D structure databases

    ProteinModelPortali Q2SLC0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 349521.HCH_01706.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC28554 ; ABC28554 ; HCH_01706 .
    GeneIDi 3839058.
    KEGGi hch:HCH_01706.
    PATRICi 22084352. VBIHahChe29232_1574.

    Phylogenomic databases

    eggNOGi COG1469.
    HOGENOMi HOG000247517.
    KOi K09007.
    OMAi AGRTTIQ.
    OrthoDBi EOG6X6RBH.

    Enzyme and pathway databases

    UniPathwayi UPA00848 ; UER00151 .
    BioCyci HCHE349521:GHAL-1641-MONOMER.

    Family and domain databases

    HAMAPi MF_01527_B. GTP_cyclohydrol_B.
    InterProi IPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view ]
    Pfami PF02649. GCHY-1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KCTC 2396.

    Entry informationi

    Entry nameiGCH4_HAHCH
    AccessioniPrimary (citable) accession number: Q2SLC0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: January 24, 2006
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3