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Protein

Soluble pyridine nucleotide transhydrogenase

Gene

sthA

Organism
Hahella chejuensis (strain KCTC 2396)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.UniRule annotation

Catalytic activityi

NADPH + NAD+ = NADP+ + NADH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi35 – 4410FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein, NAD, NADP

Enzyme and pathway databases

BioCyciHCHE349521:GHAL-2593-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Soluble pyridine nucleotide transhydrogenaseUniRule annotation (EC:1.6.1.1UniRule annotation)
Short name:
STHUniRule annotation
Alternative name(s):
NAD(P)(+) transhydrogenase [B-specific]UniRule annotation
Gene namesi
Name:sthAUniRule annotation
Ordered Locus Names:HCH_02695
OrganismiHahella chejuensis (strain KCTC 2396)
Taxonomic identifieri349521 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHahellaceaeHahella
Proteomesi
  • UP000000238 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 464464Soluble pyridine nucleotide transhydrogenasePRO_0000260236Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi349521.HCH_02695.

Structurei

3D structure databases

ProteinModelPortaliQ2SIP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DX1. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276708.
KOiK00322.
OMAiSHAFAKC.
OrthoDBiEOG6QCD6D.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
HAMAPiMF_00247. SthA.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR022962. STH.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2SIP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEYRYDVVV IGAGPAGEGA AMNAAKHGKR VAVIEDKSQV GGNCTHMGTI
60 70 80 90 100
PSKALRHAVK QIIQFNTNTM FRDIGEPRWF SFPRVLQNAE RVIGKQVKIR
110 120 130 140 150
TQFYARNRVD LYRGRASFID ENRIEVRGGL NGKEVLYGKQ IVIATGSRPY
160 170 180 190 200
LPEDVDFTHR RIYNSDSILK LSHTPRTLII YGAGVIGCEY ASIFVGLGVK
210 220 230 240 250
VDLINPGERL LSFLDGEISD ALSYHLRDNG VLVRHNEQYD SVVGDDHGVV
260 270 280 290 300
LTMKSGKRIR ADAFLWCNGR TGNTDNLGLE NIGLEPNARG QLAVDNHYRT
310 320 330 340 350
KIPHVFAAGD VIGWPSLASA AYDQGRSASS EIVKDDFFRF ITDVPTGIYT
360 370 380 390 400
IPEISSVGRT EAELTEAKVP YEVGQAFFKD LARAQITGDT VGMLKLLFHR
410 420 430 440 450
ETMELLGIHC FGDQASEIVH IGQAIMNQPG ELNTIEYFVN TTFNYPTMAE
460
AYRVAALNGL NRIF
Length:464
Mass (Da):51,435
Last modified:January 24, 2006 - v1
Checksum:i1CEE8949202C5AD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000155 Genomic DNA. Translation: ABC29482.1.
RefSeqiWP_011396551.1. NC_007645.1.

Genome annotation databases

EnsemblBacteriaiABC29482; ABC29482; HCH_02695.
KEGGihch:HCH_02695.
PATRICi22086188. VBIHahChe29232_2468.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000155 Genomic DNA. Translation: ABC29482.1.
RefSeqiWP_011396551.1. NC_007645.1.

3D structure databases

ProteinModelPortaliQ2SIP2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi349521.HCH_02695.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC29482; ABC29482; HCH_02695.
KEGGihch:HCH_02695.
PATRICi22086188. VBIHahChe29232_2468.

Phylogenomic databases

eggNOGiENOG4105DX1. Bacteria.
COG1249. LUCA.
HOGENOMiHOG000276708.
KOiK00322.
OMAiSHAFAKC.
OrthoDBiEOG6QCD6D.

Enzyme and pathway databases

BioCyciHCHE349521:GHAL-2593-MONOMER.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 2 hits.
HAMAPiMF_00247. SthA.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR022962. STH.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KCTC 2396.

Entry informationi

Entry nameiSTHA_HAHCH
AccessioniPrimary (citable) accession number: Q2SIP2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: January 24, 2006
Last modified: November 11, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.