Q2SIP2 (STHA_HAHCH) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 52.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Soluble pyridine nucleotide transhydrogenase Short name=STH EC=1.6.1.1 Alternative name(s): NAD(P)(+) transhydrogenase [B-specific] | ||||
| Gene names |
| ||||
| Organism | Hahella chejuensis (strain KCTC 2396) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 349521 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Hahellaceae › Hahella |
Protein attributes
| Sequence length | 464 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation By similarity. HAMAP MF_00247 |
| Catalytic activity | NADPH + NAD+ = NADP+ + NADH. HAMAP MF_00247 |
| Cofactor | Binds 1 FAD per subunit By similarity. HAMAP MF_00247 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00247. |
| Sequence similarities | Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | FAD Flavoprotein NAD NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cell redox homeostasis Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | NAD(P)+ transhydrogenase (B-specific) activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 464 | 464 | Soluble pyridine nucleotide transhydrogenase HAMAP MF_00247 | PRO_0000260236 | |||||
Regions | |||||||||
| Nucleotide binding | 35 – 44 | 10 | FAD By similarity | ||||||
Sequences
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References
| [1] | "Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent." Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G., Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K., Oh T.K., Kim J.F. Nucleic Acids Res. 33:7066-7073(2005) [PubMed: 16352867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KCTC 2396. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000155 Genomic DNA. Translation: ABC29482.1. |
| RefSeq | YP_433907.1. NC_007645.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 2F5Z based on UniProtKB P09622. |
| ProteinModelPortal | Q2SIP2. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q2SIP2. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3839006. |
| GenomeReviews | Gene locus HCH_02695 in contig CP000155_GR. |
| KEGG | hch:HCH_02695. |
| NMPDR | fig|349521.5.peg.2402. |
| PATRIC | 22086188. VBIHahChe29232_2468. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG1249. |
| HOGENOM | HBG515043. |
| OMA | RSTHFDA. |
| PhylomeDB | Q2SIP2. |
| ProtClustDB | PRK05249. |
Enzyme and pathway databases | |
| BioCyc | HCHE349521:HCH_02695-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00247. SthA. [Tree] |
| InterPro | IPR016156. FAD/NAD-linked_Rdtase_dimer. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR004099. Pyr_nucl-diS_OxRdtase_dimer. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR022962. STH. [Graphical view] |
| Gene3D | G3DSA:3.30.390.30. Pyr_redox_dim. 1 hit. |
| KO | K00322. |
| Pfam | PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. PF02852. Pyr_redox_dim. 1 hit. [Graphical view] |
| PRINTS | PR00368. FADPNR. |
| SUPFAM | SSF55424. FAD/NAD-linked_reductase_dimer. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | STHA_HAHCH | ||||||||
| Accession | Primary (citable) accession number: Q2SIP2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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