Reviewed, UniProtKB/Swiss-Prot Q2SHX7 (SDHD_HAHCH)

Names and origin

Protein names

Recommended name:
    Probable D-serine dehydratase
    EC=4.3.1.18
Alternative name(s):
    D-serine deaminase
      Short name=DSD

Gene names

Name:	dsdA
Ordered Locus Names:	HCH_02978

Organism

Hahella chejuensis (strain KCTC 2396) [Complete proteome] [HAMAP]

Taxonomic identifier

349521 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Hahellaceae › Hahella

Protein attributes

Sequence length	437 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-serine = pyruvate + NH3. HAMAP MF_01030
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the serine/threonine dehydratase family. DsdA subfamily.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	D-amino acid metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	D-serine ammonia-lyase activity Inferred from electronic annotation. Source: EC hydro-lyase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 437	437	Probable D-serine dehydratase HAMAP MF_01030		PRO_0000291733
Amino acid modifications
	Modified residue	106	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2SHX7-1 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: D13DF85ADB496BB0	FASTA	437	47,323
	10 20 30 40 50 60 MNPLSIAQDE LKAIQSSQPI VWLNRNYQNP ASAPATPNVD ALYAAEARLK RFAPLLQRLF 70 80 90 100 110 120 PELEPSHGLI ESSLIQADRL NNRINPVGGL LFLKADHDLP VAGSVKARGG IHEVLCFAES 130 140 150 160 170 180 LALTHGVLKD VDSDYCTLAS QSARDLFSKH TITVGSTGNL GLSIGVIGSA LGFKTVVHMS 190 200 210 220 230 240 SDAKEWKMER LRKRGVRVVE HDADYGAALE AGRLETIADP CGYFVDDERS PNLFMGYAVA 250 260 270 280 290 300 AKRLQAQLEA LNIKVDADHP LFVYLPAGVG GAPGGITYGL KHIFNDHVHC FFAEPVQSPC 310 320 330 340 350 360 MLLGMAGAPG AAPTSIYELD LKNRTDADGL AVGAASQWVC DATRNLLSGV YTATDEQLYQ 370 380 390 400 410 420 QLYLLKDLEN IEVEPSAAIG CLGPAMLTSE AGQKYLDSHR LSHRMENSVH IPWLTGGSFV 430 PDEEYQRYLA KAVNVST

References

[1]

"Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent." Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G., Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K., Oh T.K., Kim J.F. Nucleic Acids Res. 33:7066-7073(2005) [PubMed: 16352867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000155 Genomic DNA. Translation: ABC29747.1.
RefSeq	YP_434172.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3840584.
GenomeReviews	Gene locus HCH_02978 in contig CP000155_GR.
KEGG	hch:HCH_02978.
NMPDR	fig|349521.5.peg.2640.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2SHX7.
OMA	Q2SHX7. DHPLFVY.
Enzyme and pathway databases
BioCyc	HCHE349521:HCH_02978-MON.
Family and domain databases
HAMAP	MF_01030. [Tree]
InterPro	IPR011780. D_Ser_am_lyase. IPR001926. PyrdxlP-dep_enz_bsu. IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS. [Graphical view]
PANTHER	PTHR10314:SF9. D_Ser_am_lyase. 1 hit.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
TIGRFAMs	TIGR02035. D_Ser_am_lyase. 1 hit.
PROSITE	PS00165. DEHYDRATASE_SER_THR. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SDHD_HAHCH

Accession

Primary (citable) accession number: Q2SHX7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	January 24, 2006
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)