Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2SBR1

- LPXB_HAHCH

UniProt

Q2SBR1 - LPXB_HAHCH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Hahella chejuensis (strain KCTC 2396)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciHCHE349521:GHAL-5047-MONOMER.
UniPathwayiUPA00359; UER00481.

Protein family/group databases

CAZyiGT19. Glycosyltransferase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
Gene namesi
Name:lpxBUniRule annotation
Ordered Locus Names:HCH_05238
OrganismiHahella chejuensis (strain KCTC 2396)
Taxonomic identifieri349521 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHahellaceaeHahella
ProteomesiUP000000238: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 396396Lipid-A-disaccharide synthasePRO_0000255187Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi349521.HCH_05238.

Structurei

3D structure databases

ProteinModelPortaliQ2SBR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018003.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2SBR1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTPISERPIR IGIVAGEASG DLLGAGLMQE IKALYPQATF EGIGGERMLK
60 70 80 90 100
EGFNTFFQME RLSIMGLVEV LGRLPELLAM RRRIVDHFTA TPPDLFLGID
110 120 130 140 150
SPDFTIGIEL KLRQAGIKTA HYVSPSVWAW RQNRVFKIAK AVDLMLTLLP
160 170 180 190 200
FEARFYREHN VPVKFVGHPL AEIIPLHPDK VAMRHELGID ASGEVIAVLP
210 220 230 240 250
GSRGGEVSRL GPTFIETIAW LHQRRPDVRF VIPAANQARK TQIEQQLQSH
260 270 280 290 300
GGRLPVTLID QHSRECMMAA DAILLASGTA TLEAMLVKRP MVVAYKLATL
310 320 330 340 350
SYWIMRRLLK AKYISLPNLL ADKALVPELI QNDATPAKLG EALLKELNVE
360 370 380 390
RRRSLEDEFE GLHKLIRQNA SVAAAQAVAE LIEKGRVATH DAREGH
Length:396
Mass (Da):44,033
Last modified:January 24, 2006 - v1
Checksum:iB231BF9EA1441D0F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000155 Genomic DNA. Translation: ABC31913.1.
RefSeqiYP_436338.1. NC_007645.1.

Genome annotation databases

EnsemblBacteriaiABC31913; ABC31913; HCH_05238.
GeneIDi3839772.
KEGGihch:HCH_05238.
PATRICi22090834. VBIHahChe29232_4768.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000155 Genomic DNA. Translation: ABC31913.1 .
RefSeqi YP_436338.1. NC_007645.1.

3D structure databases

ProteinModelPortali Q2SBR1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 349521.HCH_05238.

Protein family/group databases

CAZyi GT19. Glycosyltransferase Family 19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC31913 ; ABC31913 ; HCH_05238 .
GeneIDi 3839772.
KEGGi hch:HCH_05238.
PATRICi 22090834. VBIHahChe29232_4768.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018003.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci HCHE349521:GHAL-5047-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KCTC 2396.

Entry informationi

Entry nameiLPXB_HAHCH
AccessioniPrimary (citable) accession number: Q2SBR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: January 24, 2006
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3