Q2S8Z8 (EFTU_HAHCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor Tu
Short name=EF-Tu

Gene names

Name:	tuf1
Ordered Locus Names:	HCH_06219
AND
Name:	tuf2
Ordered Locus Names:	HCH_06231

Organism

Hahella chejuensis (strain KCTC 2396) [Complete proteome] [HAMAP]

Taxonomic identifier

349521 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Hahellaceae › Hahella › Hahella chejuensis

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	GTP-binding Nucleotide-binding
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Elongation factor Tu HAMAP-Rule MF_00118		PRO_0000337402
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity
	Nucleotide binding	81 – 85	5	GTP By similarity
	Nucleotide binding	136 – 139	4	GTP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2S8Z8 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 9F66E12FCF3ED930	FASTA	397	43,243
	10 20 30 40 50 60 MAKEKFERSK PHVNVGTIGH VDHGKTTLTA ALTRVCSEVW GGQAVAFDGI DNAPEEKARG 70 80 90 100 110 120 ITIATSHVEY ESPIRHYAHV DCPGHADYVK NMITGAAQMD GAILVCSAAD GPMPQTREHI 130 140 150 160 170 180 LLARQVGVPY IVVFLNKADM VDDEELLELV EMEVRDLLSQ YEFPGDDTPI IVGSALLALE 190 200 210 220 230 240 GKDDNGMGTS AVKKLVETLD AYIPEPERAI DKPFLMPIED VFSISGRGTV VTGRVERGIV 250 260 270 280 290 300 RVGEEVEIVG IKDTTKTTCT GVEMFRKLLD EGRAGENVGV LLRGTKRDDV ERGQVLAKPG 310 320 330 340 350 360 TITPHTVFES EVYVLSKDEG GRHTPFFKGY RPQFYFRTTD VTGACELPEG VEMVMPGDNV 370 380 390 KMKVSLIAPI AMEEGLRFAI REGGRTVGAG VVAKIFE

References

[1]

"Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent." Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G., Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K., Oh T.K., Kim J.F. Nucleic Acids Res. 33:7066-7073(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KCTC 2396.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000155 Genomic DNA. Translation: ABC32864.1. CP000155 Genomic DNA. Translation: ABC32876.1.
RefSeq	YP_437289.1. NC_007645.1. YP_437301.1. NC_007645.1.
3D structure databases
HSSP	HSSP built from PDB template 1OB2 based on UniProtKB P0A6N1.
ProteinModelPortal	Q2S8Z8.
SMR	Q2S8Z8. Positions 2-396.
ModBase	Search...
Protein-protein interaction databases
STRING	349521.HCH_06231.
Proteomic databases
PRIDE	Q2S8Z8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3840052. 3840209.
KEGG	hch:HCH_06219. hch:HCH_06231.
PATRIC	22092630. VBIHahChe29232_5655.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0050.
HOGENOM	HOG000229290.
KO	K02358.
OMA	CEFVGYN.
ProtClustDB	PRK00049.
Enzyme and pathway databases
BioCyc	HCHE349521:GHAL-6022-MONOMER. HCHE349521:GHAL-6034-MONOMER.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTU_HAHCH

Accession

Primary (citable) accession number: Q2S8Z8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	January 24, 2006
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program