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Q2S8W1 (G6PI_HAHCH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:HCH_06266
OrganismHahella chejuensis (strain KCTC 2396) [Complete proteome] [HAMAP]
Taxonomic identifier349521 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHahellaceaeHahella

Protein attributes

Sequence length557 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 557557Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252623

Sites

Active site3591Proton donor By similarity
Active site3901 By similarity
Active site5181 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2S8W1 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 11BB65E44D07A707

FASTA55761,339
        10         20         30         40         50         60 
MQDTPQTLND KAKESWRALQ QHAADTANDH ILDYFHSDPS RVQSYSLTAA GLTLDYSKNR 

        70         80         90        100        110        120 
ANSITLEKLV KLAEDAGMKR SIDAMFAGEP INHTEGRAVL HTALRDSSDT PVLVDGQDIK 

       130        140        150        160        170        180 
PEIRSALAQM ERFVSKVHRG EWLGYSGKPI NDVVSIGIGG SYLGPRVAVE ALRPYWQENI 

       190        200        210        220        230        240 
RCHFVSNVDG SDIAYTLENL NPETTLFIVQ SKSFTTQETL ANSMTAREWY LREGGSEAGL 

       250        260        270        280        290        300 
SKHFVAVSSN VQRARDFGID AENVFPMWDW VGGRYSLWSA IGLPIALQVD MKAFRELLAG 

       310        320        330        340        350        360 
AEAMDQHFKT APLEQNMPVL MGMLGIWYHN FLGADSYVIL PYDQTLENLP AHLQQVDMES 

       370        380        390        400        410        420 
NGKGVNRAGI GVDYATGPII WGGAGTNGQH AYHQLLHQGT RWTPADFILP LKTHKPAGRH 

       430        440        450        460        470        480 
HAMLASNCFA QSQALMCGKS LEKARQELLD AGMSSERAEE LAPHKVIPGN RPSNTLVMDE 

       490        500        510        520        530        540 
INPHTLGALI ALYEQKVFVQ GVIWNLNSFD QWGVELGKQL SDSILPMLLD TGASTDALDP 

       550 
SSAALVERFR RANGSGS 

« Hide

References

[1]"Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent."
Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G., Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K., Oh T.K., Kim J.F.
Nucleic Acids Res. 33:7066-7073(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KCTC 2396.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000155 Genomic DNA. Translation: ABC32913.1.
RefSeqYP_437338.1. NC_007645.1.

3D structure databases

ProteinModelPortalQ2S8W1.
SMRQ2S8W1. Positions 13-553.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349521.HCH_06266.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC32913; ABC32913; HCH_06266.
GeneID3844215.
KEGGhch:HCH_06266.
PATRIC22092742. VBIHahChe29232_5701.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycHCHE349521:GHAL-6067-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_HAHCH
AccessionPrimary (citable) accession number: Q2S8W1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: January 24, 2006
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways