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Q2S6X2

- GLSA_HAHCH

UniProt

Q2S6X2 - GLSA_HAHCH

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Protein
Glutaminase
Gene
glsA, HCH_06987
Organism
Hahella chejuensis (strain KCTC 2396)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei68 – 681Substrate By similarity
Binding sitei118 – 1181Substrate By similarity
Binding sitei162 – 1621Substrate By similarity
Binding sitei169 – 1691Substrate By similarity
Binding sitei193 – 1931Substrate By similarity
Binding sitei244 – 2441Substrate By similarity
Binding sitei262 – 2621Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciHCHE349521:GHAL-6758-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:HCH_06987
OrganismiHahella chejuensis (strain KCTC 2396)
Taxonomic identifieri349521 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHahellaceaeHahella
ProteomesiUP000000238: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308GlutaminaseUniRule annotation
PRO_0000336029Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi349521.HCH_06987.

Structurei

3D structure databases

ProteinModelPortaliQ2S6X2.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2S6X2-1 [UniParc]FASTAAdd to Basket

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MKLQKSELPA LLERIYSEVT PLYGVGKTAD YIPPLSRVNP RQFGMAIRFV    50
DGDEFTVGQA STPFSIQSIS KLFALMLALD IVGDDLWKRV GREPSGMRFN 100
SLLQLENENG IPRNPFINAG AIVVTDTIVN HSASPVKRLE QFMASLSGNV 150
FNRYDPEVYV AEARTGYRNA AIANLLKALG NLEGEVDVVL DSYYKQCSMT 200
MSCLDLARAT ESLANKGKSS FRTQFHGERM DKRVNALMLT CGLYDAAGNF 250
AYQVGLPAKS GVGGGIVAVL PGYFSVAVWS PELDSYGNSV LGQKALELLT 300
HYTSSSIF 308
Length:308
Mass (Da):33,647
Last modified:January 24, 2006 - v1
Checksum:i8517B88423066C91
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000155 Genomic DNA. Translation: ABC33602.1.
RefSeqiYP_438027.1. NC_007645.1.

Genome annotation databases

EnsemblBacteriaiABC33602; ABC33602; HCH_06987.
GeneIDi3839719.
KEGGihch:HCH_06987.
PATRICi22094068. VBIHahChe29232_6362.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000155 Genomic DNA. Translation: ABC33602.1 .
RefSeqi YP_438027.1. NC_007645.1.

3D structure databases

ProteinModelPortali Q2S6X2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 349521.HCH_06987.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC33602 ; ABC33602 ; HCH_06987 .
GeneIDi 3839719.
KEGGi hch:HCH_06987.
PATRICi 22094068. VBIHahChe29232_6362.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci HCHE349521:GHAL-6758-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KCTC 2396.

Entry informationi

Entry nameiGLSA_HAHCH
AccessioniPrimary (citable) accession number: Q2S6X2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: January 24, 2006
Last modified: June 11, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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