Q2S5H3 (Q2S5H3_SALRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL ABC44706.1
EC=1.5.1.3 EMBL ABC44706.1

Gene names

Name:	folA EMBL ABC44706.1
Ordered Locus Names:	SRU_0412

Organism

Salinibacter ruber (strain DSM 13855 / M31)

Taxonomic identifier

309807 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Salinibacter

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ABC44706.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2S5H3 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 8284253614274A5F	FASTA	186	20,697
	10 20 30 40 50 60 MAFSSASLPT FDLAAALMPE LVIIAAVAED NRVIGQDKDL PWHIPEDLKR FKQLTTGHPL 70 80 90 100 110 120 LMGRRTFESI VHQFGGPLPD RKMVVLTTQD DYEAYPEVDT YASVDAALAA LPDDATVFIG 130 140 150 160 170 180 GGESVYEQFL PHADRLELTL VEGAYEGDTF FPPFEHLIGD VFEETAVDAR DGFRFVTYER KNVDVD

References

[1]

"The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea." Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H., Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K., Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L., Legault B., Rodriguez-Valera F. Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005) [PubMed: 16330755] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13855 / M31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000159 Genomic DNA. Translation: ABC44706.1.
RefSeq	YP_444558.1. NC_007677.1.
3D structure databases
ProteinModelPortal	Q2S5H3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2S5H3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3851780.
GenomeReviews	Gene locus SRU_0412 in contig CP000159_GR.
KEGG	sru:SRU_0412.
NMPDR	fig|309807.5.peg.378.
PATRIC	23423163. VBISalRub86502_0432.
TIGR	SRU_0412.
Phylogenomic databases
eggNOG	COG0262.
HOGENOM	HBG665708.
OMA	WVETARE.
PhylomeDB	Q2S5H3.
ProtClustDB	CLSK2774240.
Enzyme and pathway databases
BioCyc	SRUB309807:SRU_0412-MONOMER.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2S5H3_SALRD

Accession

Primary (citable) accession number: Q2S5H3

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)