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Q2S515 (Q2S515_SALRD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site891Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site3161Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1861Substrate By similarity HAMAP-Rule MF_01201
Binding site3641Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue891N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q2S515 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 52CAE22EEA0C2350

FASTA45047,052
        10         20         30         40         50         60 
MGCEAGGRGE HVRRAIGAEG FGNHRPGRRL SCACSLIFAR SPVPFAIDRS PHTVGAAPVT 

        70         80         90        100        110        120 
ATVDLAAIRH NAGVLQERAG GADVMAIIKA DAYGHGVRPV AQAAYEAGIR HYGVARLPEG 

       130        140        150        160        170        180 
VHLREAGHGG RILVLGAPAP TQLPRYAEYD LDLTVSSADV AAAVVRHASP EAPLRVHVTV 

       190        200        210        220        230        240 
DTGMGRLGLA PDDVPAVMTR LADASGVRLA GLWTHFATAD APGSSFAQTQ LDRFRAVVGA 

       250        260        270        280        290        300 
VDVDVEHVHA ANTGGLLTIG APTHEFDASL VRSGIALYGL AATPELSARL DLRPAMRLAA 

       310        320        330        340        350        360 
RVTHLKTVPA GTPISYGAQW EAPRRTRIAT LGIGYGDGYP RRCSGRASVR IGGASCPIVG 

       370        380        390        400        410        420 
TICMDMCMVD LGPPNEAPAT RVDRGDEAVL FGPAGPTAYD VAQWSDTIPY EILCGVSPRV 

       430        440        450 
PRRHVNCTDE NGTDDMRAPS RLTRPTASGG 

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References

[1]"The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea."
Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H., Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K., Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L., Legault B., Rodriguez-Valera F.
Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13855 / M31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000159 Genomic DNA. Translation: ABC45941.1.
RefSeqYP_444716.1. NC_007677.1.

3D structure databases

ProteinModelPortalQ2S515.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING309807.SRU_0573.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC45941; ABC45941; SRU_0573.
GeneID3852801.
KEGGsru:SRU_0573.
PATRIC23423495. VBISalRub86502_0597.

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAITMDQLM.
OrthoDBEOG6PP9NJ.
PhylomeDBQ2S515.
ProtClustDBCLSK2775086.

Enzyme and pathway databases

BioCycSRUB309807:GJJD-572-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2S515_SALRD
AccessionPrimary (citable) accession number: Q2S515
Entry history
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: February 19, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)