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Q2S515

- Q2S515_SALRD

UniProt

Q2S515 - Q2S515_SALRD

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Protein

Alanine racemase

Gene
alr, SRU_0573
Organism
Salinibacter ruber (strain DSM 13855 / M31)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei89 – 891Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei186 – 1861Substrate By similarityUniRule annotation
Active sitei316 – 3161Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei364 – 3641Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciSRUB309807:GJJD-572-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:SRU_0573Imported
OrganismiSalinibacter ruber (strain DSM 13855 / M31)Imported
Taxonomic identifieri309807 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidetes Order II. Incertae sedisRhodothermaceaeSalinibacter
ProteomesiUP000008674: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei89 – 891N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi309807.SRU_0573.

Structurei

3D structure databases

ProteinModelPortaliQ2S515.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiRIGISIY.
OrthoDBiEOG6PP9NJ.
PhylomeDBiQ2S515.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2S515-1 [UniParc]FASTAAdd to Basket

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MGCEAGGRGE HVRRAIGAEG FGNHRPGRRL SCACSLIFAR SPVPFAIDRS    50
PHTVGAAPVT ATVDLAAIRH NAGVLQERAG GADVMAIIKA DAYGHGVRPV 100
AQAAYEAGIR HYGVARLPEG VHLREAGHGG RILVLGAPAP TQLPRYAEYD 150
LDLTVSSADV AAAVVRHASP EAPLRVHVTV DTGMGRLGLA PDDVPAVMTR 200
LADASGVRLA GLWTHFATAD APGSSFAQTQ LDRFRAVVGA VDVDVEHVHA 250
ANTGGLLTIG APTHEFDASL VRSGIALYGL AATPELSARL DLRPAMRLAA 300
RVTHLKTVPA GTPISYGAQW EAPRRTRIAT LGIGYGDGYP RRCSGRASVR 350
IGGASCPIVG TICMDMCMVD LGPPNEAPAT RVDRGDEAVL FGPAGPTAYD 400
VAQWSDTIPY EILCGVSPRV PRRHVNCTDE NGTDDMRAPS RLTRPTASGG 450
Length:450
Mass (Da):47,052
Last modified:January 24, 2006 - v1
Checksum:i52CAE22EEA0C2350
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000159 Genomic DNA. Translation: ABC45941.1.
RefSeqiYP_444716.1. NC_007677.1.

Genome annotation databases

EnsemblBacteriaiABC45941; ABC45941; SRU_0573.
GeneIDi3852801.
KEGGisru:SRU_0573.
PATRICi23423495. VBISalRub86502_0597.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000159 Genomic DNA. Translation: ABC45941.1 .
RefSeqi YP_444716.1. NC_007677.1.

3D structure databases

ProteinModelPortali Q2S515.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 309807.SRU_0573.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC45941 ; ABC45941 ; SRU_0573 .
GeneIDi 3852801.
KEGGi sru:SRU_0573.
PATRICi 23423495. VBISalRub86502_0597.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi RIGISIY.
OrthoDBi EOG6PP9NJ.
PhylomeDBi Q2S515.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci SRUB309807:GJJD-572-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13855 / M31.

Entry informationi

Entry nameiQ2S515_SALRD
AccessioniPrimary (citable) accession number: Q2S515
Entry historyi
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: July 9, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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