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Q2S3Y8 (PSD_SALRD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:SRU_0961
OrganismSalinibacter ruber (strain DSM 13855 / M31)
Taxonomic identifier309807 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Salinibacter

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 168168Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000262267
Chain169 – 22759Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000262268

Sites

Site168 – 1692Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1691Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2S3Y8 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: C9CE3E239C0C1050

FASTA22724,582
        10         20         30         40         50         60 
MLTGGALWVD AWLWRGPMLT LAVGGLAFVL YFFRDPERTP PADALEAGIV APADGRVVEI 

        70         80         90        100        110        120 
AEEDDPLYLE GPARRISIFL SPLDVHVNRV PARGVIEHAE YRPGDYLVAW HPKASEKNER 

       130        140        150        160        170        180 
SEFGLRHPTG TKLLFKQIAG AVARRIEYDL REGDTVETGA RFGIVKFGSR MDLLVPPSVE 

       190        200        210        220 
LHAKEGQVVR AGTTVLGRIP TPESGRSSSA EATAAPSASS ARRSSAS

« Hide

References

[1]"The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea."
Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H., Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K., Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L., Legault B., Rodriguez-Valera F.
Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005) [PubMed: 16330755] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13855 / M31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000159 Genomic DNA. Translation: ABC44517.1.
RefSeqYP_445093.1. NC_007677.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2S3Y8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3853049.
GenomeReviewsGene locus SRU_0961 in contig CP000159_GR.
KEGGsru:SRU_0961.
NMPDRfig|309807.5.peg.896.
PATRIC23424303. VBISalRub86502_0996.
TIGRSRU_0961.

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG541103.
OMAIFMSVFN.
PhylomeDBQ2S3Y8.
ProtClustDBCLSK2774123.

Enzyme and pathway databases

BioCycSRUB309807:SRU_0961-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePSD_SALRD
AccessionPrimary (citable) accession number: Q2S3Y8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: January 24, 2006
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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