Q2S3D2 (Q2S3D2_SALRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-oxoglutarate dehydrogenase, E1 component EMBL ABC45112.1
EC=1.2.4.2 EMBL ABC45112.1

Gene names

Name:	sucA EMBL ABC45112.1
Ordered Locus Names:	SRU_1173

Organism

Salinibacter ruber (strain DSM 13855 / M31)

Taxonomic identifier

309807 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Salinibacter

Protein attributes

Sequence length	1243 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Molecular function	Oxidoreductase EMBL ABC45112.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2S3D2 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 8369084273B3305E	FASTA	1,243	138,870
	10 20 30 40 50 60 MSSLGFNTGY IEELYKQYQD DPDSVSESWR EFFADYDPDA SFIPVDRTTA GDGEATTPPE 70 80 90 100 110 120 EPTEPEPTDR DSSPDASSAP PAEADDGVVE PLRPASAPAV DEDQADVTAM TGPSAKVVEN 130 140 150 160 170 180 MEDSLGIPTA TSARTIPVKL LDENRNLLND YQKQVGGEKV SYTHIIAYAM VQAMQKYPDM 190 200 210 220 230 240 NTTFRRNEDG TPEHVKPDQI NLGLAIDVER RGERTLLVPN LKDAGSLSFA EFLGTYNNIV 250 260 270 280 290 300 GRALGGDLDL SDFQGTTATL TNPGMIGTSM SVARLMPGQG VIMGAGAIDF PPEYRGYDSE 310 320 330 340 350 360 VASKAGVSPV MTLTSTYDHR VIQGATSGAF LNHIEELLTG NHDFYQRIFS DLGVPYQPFR 370 380 390 400 410 420 MATDSTPQLG RSRPQDELDM TEKQAAVLQL IRAYRVRGHL QADINPLGYE WQYHEELDPA 430 440 450 460 470 480 TYGLTVWDLD REFITGGLGG EDKLPLREIL SILRKSYTSK VGTAFMHISD PEEKTWIQNR 490 500 510 520 530 540 IEPMRNAGSP SEEERHRIVQ KLNAAEAFER FLHTKYIGHK RFSLEGSETM IPLIDTLLSD 550 560 570 580 590 600 AADEGVEEVV MGMAHRGRLN VLANIIGKPY EEIFSKFEGN IDPNTTQGSG DVKYHLGAEG 610 620 630 640 650 660 DVTSPDGNEI SVTLASNPSH LEAVNPVVEG MSRAKQNLLR DEHPEAAEDD YHDAVMPLLI 670 680 690 700 710 720 HGDAGFAGQG VVAETLNLSK LRGYTTGGTV HLVINNQIGF TTPPGDARSS TYATDLARAI 730 740 750 760 770 780 EAPIFHVNGD DPETCVRIAR LAFEYRQRFN KDVVIDMMCY RVHGHNEGDE PTFTQPLLYE 790 800 810 820 830 840 KIEEKRSPRK LYTEMLLRRG EIEPDEAEQM LDDYRGRLQE AFERTKDLEE KDADEALEER 850 860 870 880 890 900 VQRTADDRLP PVDTTAEREH LERVVEVLTD FPDDFNVHRK LERLFGKRDD LFYDEKRIDW 910 920 930 940 950 960 AFSETLAFGS LLQEGTRVRL SGQDSRRATF SQRHAVLIDQ ETGAEYTPLN NLTDDQERLL 970 980 990 1000 1010 1020 IYDSLLSEYA VAGFEYGYSV VDKNALTCWE AQFGDFANGA EIVWDQFVSA AEEKWGQTSG 1030 1040 1050 1060 1070 1080 LVALLPHAYE GQGPEHSSAR LERFLQLCAE QNMIVANFST PANYFHALRR QVKRDVKKPL 1090 1100 1110 1120 1130 1140 IIMTPKSLLR HPKCVSTPED LMEGGVQEII PAEADPAGTM RHILCSGKVY YDLVTALEDT 1150 1160 1170 1180 1190 1200 DRRDEIAITR LEQFYPFPES DLQEELERYA EADETVWVQE EPQNMGAWSF VSPRFETLLD 1210 1220 1230 1240 EIHGPCEQRI QYVGRPASAS PATGSAKVHD REQEQLVGDA LGL

References

[1]

"The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea." Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H., Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K., Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L., Legault B., Rodriguez-Valera F. Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005) [PubMed: 16330755] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13855 / M31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000159 Genomic DNA. Translation: ABC45112.1.
RefSeq	YP_445299.1. NC_007677.1.
3D structure databases
ProteinModelPortal	Q2S3D2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2S3D2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3850786.
GenomeReviews	Gene locus SRU_1173 in contig CP000159_GR.
KEGG	sru:SRU_1173.
NMPDR	fig|309807.5.peg.1094.
PATRIC	23424751. VBISalRub86502_1217.
TIGR	SRU_1173.
Phylogenomic databases
eggNOG	COG0567.
HOGENOM	HBG289950.
OMA	EGDEPAF.
PhylomeDB	Q2S3D2.
ProtClustDB	PRK12270.
Enzyme and pathway databases
BioCyc	SRUB309807:SRU_1173-MONOMER.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
KO	K00164.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2S3D2_SALRD

Accession

Primary (citable) accession number: Q2S3D2

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)