ID   Q2S2J4_SALRD            Unreviewed;       524 AA.
AC   Q2S2J4;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   SubName: Full=Glycerol-3-phosphate dehydrogenase, anaerobic {ECO:0000313|EMBL:ABC44790.1};
DE            EC=1.1.5.3 {ECO:0000313|EMBL:ABC44790.1};
GN   Name=glpA {ECO:0000313|EMBL:ABC44790.1};
GN   OrderedLocusNames=SRU_1463 {ECO:0000313|EMBL:ABC44790.1};
OS   Salinibacter ruber (strain DSM 13855 / M31).
OC   Bacteria; Rhodothermota; Rhodothermia; Rhodothermales; Salinibacteraceae;
OC   Salinibacter.
OX   NCBI_TaxID=309807 {ECO:0000313|EMBL:ABC44790.1, ECO:0000313|Proteomes:UP000008674};
RN   [1] {ECO:0000313|EMBL:ABC44790.1, ECO:0000313|Proteomes:UP000008674}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13855 / CECT 5946 / M31
RC   {ECO:0000313|Proteomes:UP000008674};
RX   PubMed=16330755; DOI=10.1073/pnas.0509073102;
RA   Mongodin E.F., Nelson K.E., Daugherty S., Deboy R.T., Wister J., Khouri H.,
RA   Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K.,
RA   Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L.,
RA   Legault B., Rodriguez-Valera F.;
RT   "The genome of Salinibacter ruber: convergence and gene exchange among
RT   hyperhalophilic bacteria and archaea.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the FAD-dependent glycerol-3-phosphate
CC       dehydrogenase family. {ECO:0000256|ARBA:ARBA00007330}.
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DR   EMBL; CP000159; ABC44790.1; -; Genomic_DNA.
DR   RefSeq; WP_011404213.1; NC_007677.1.
DR   RefSeq; YP_445587.1; NC_007677.1.
DR   AlphaFoldDB; Q2S2J4; -.
DR   STRING; 309807.SRU_1463; -.
DR   EnsemblBacteria; ABC44790; ABC44790; SRU_1463.
DR   KEGG; sru:SRU_1463; -.
DR   PATRIC; fig|309807.25.peg.1518; -.
DR   eggNOG; COG0578; Bacteria.
DR   HOGENOM; CLU_015740_4_1_10; -.
DR   OrthoDB; 9766796at2; -.
DR   Proteomes; UP000008674; Chromosome.
DR   GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
DR   GO; GO:0004368; F:glycerol-3-phosphate dehydrogenase (quinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.8.870; Alpha-glycerophosphate oxidase, cap domain; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR031656; DAO_C.
DR   InterPro; IPR038299; DAO_C_sf.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000447; G3P_DH_FAD-dep.
DR   PANTHER; PTHR11985; GLYCEROL-3-PHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11985:SF15; GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16901; DAO_C; 1.
DR   PRINTS; PR01001; FADG3PDH.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS00978; FAD_G3PDH_2; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:ABC44790.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008674}.
FT   DOMAIN          18..374
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          417..495
FT                   /note="Alpha-glycerophosphate oxidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16901"
SQ   SEQUENCE   524 AA;  57763 MW;  907A5FB866B2E598 CRC64;
     MDRTQGIEAL QSRQTPWDFV IIGGGATGLG CAVDAAARGY DTLLLEMHDF AKATSSRSTK
     LVHGGVRYLE QGNVSLVFEA LKERERLQDN APHLVSNLPF VVPSYKWWEA PYYGIGMKVY
     DLLAGSQNFG RSQYLDRNQT IERLPTVETD GLRGGILYFD GQFDDTRLAV NMAQTADEQG
     GVLLNYMKAT DLKKTNGAVD GVVAECQETG ATFDIEARSV INATGIFTDT IRQMDDPSAG
     TTLRPSRGTH IVLDKSFLPG DSAIMVPKTD DGRVLFAIPW HDRVVVGTTE AEVDEVSMEP
     TPGHEELDFL LTHAQRYLAK DPGPEDVRSV YAGIRPLVAP PGSNGDTSDI SREHQLNVSD
     SGLVTISGGK WTTYRKMAED TIDRAARHAE LARRPSQTDD LRLHGWHQNP EQFGDLALYG
     ADAEALGGLM EEHPHLQTPL DERLPIRAGQ VVWAARHEMA RTVEDVLARR TRCLLLDAQA
     SIDVAPRVAE LMAEERDLPP SWVDDQVEAF TEVARNYLMP SIPA
//