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Q2S2I6 (Q2S2I6_SALRD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpK HAMAP MF_00186 EMBL ABC43677.1
Ordered Locus Names:SRU_1471
OrganismSalinibacter ruber (strain DSM 13855 / M31)
Taxonomic identifier309807 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Salinibacter

Protein attributes

Sequence length526 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding408 – 4125ATP By similarity HAMAP MF_00186

Sites

Binding site111Substrate By similarity HAMAP MF_00186
Binding site151ATP By similarity HAMAP MF_00186
Binding site811Substrate By similarity HAMAP MF_00186
Binding site1331Substrate By similarity HAMAP MF_00186
Binding site2421Substrate By similarity HAMAP MF_00186
Binding site2641ATP By similarity HAMAP MF_00186
Binding site3071ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
Q2S2I6 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 6955A4FCC750C0BF

FASTA52657,176
        10         20         30         40         50         60 
MQYILALDQG TTSSRSILFD TQGQVQAVAQ KEFEQHYPQP GWVEHDANEI WSTQMGTASE 

        70         80         90        100        110        120 
AMSRANVEAE DLAAIGITNQ RETTVVWDRA TGTPIHNAIV WQDRRTSGLC DRLKDRGHLD 

       130        140        150        160        170        180 
LIQEKTGLII DAYFSGTKIK WLLDNVDGAR ERAENGELAF GTVDSWLVWR MTNGKRHVTD 

       190        200        210        220        230        240 
ATNASRTLLY NIHEGAWDPE LLDILDIPPS MLPDVRDSSE VYGTTQGGPF DEEVPIAGIA 

       250        260        270        280        290        300 
GDQQAALFGQ MCTTPGLGKN TYGTGAFLLQ NTGETAVTSE HNLLTTIAYQ IDGTTYYALE 

       310        320        330        340        350        360 
GSIFVAGAVV QWLRDELKMI REAAEVERLA RTVDDNGGVY FVPAFTGLGA PYWDQYARGT 

       370        380        390        400        410        420 
ISGLTRGANR GHLARAAIES MAYQVADVID AMEADSGIET TELGADGGAA ANDLLLQFQS 

       430        440        450        460        470        480 
DILDIPVVRP KILETTALGA AYLAGLAVGY WDSQSEIQDQ WELDQMFTPS MPQNRVETLR 

       490        500        510        520 
TGWSKALDRA RAWESPDSSE AAPQAADVST NATSTAPAGE ESPAAS

« Hide

References

[1]"The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea."
Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H., Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K., Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L., Legault B., Rodriguez-Valera F.
Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005) [PubMed: 16330755] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13855 / M31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000159 Genomic DNA. Translation: ABC43677.1.
RefSeqYP_445595.1. NC_007677.1.

3D structure databases

ProteinModelPortalQ2S2I6.
SMRQ2S2I6. Positions 2-495.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2S2I6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3850493.
GenomeReviewsGene locus SRU_1471 in contig CP000159_GR.
KEGGsru:SRU_1471.
NMPDRfig|309807.5.peg.1388.
PATRIC23425375. VBISalRub86502_1527.
TIGRSRU_1471.

Phylogenomic databases

eggNOGCOG0554.
HOGENOMHBG511469.
OMAALYGQLC.
PhylomeDBQ2S2I6.
ProtClustDBCLSK2773563.

Enzyme and pathway databases

BioCycSRUB309807:SRU_1471-MONOMER.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2S2I6_SALRD
AccessionPrimary (citable) accession number: Q2S2I6
Entry history
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info