SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2S1L8

- SYE_SALRD

UniProt

Q2S1L8 - SYE_SALRD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate--tRNA ligase

Gene
gltX, SRU_1796
Organism
Salinibacter ruber (strain DSM 13855 / M31)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity.UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei258 – 2581ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSRUB309807:GJJD-1794-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligase (EC:6.1.1.17)
Alternative name(s):
Glutamyl-tRNA synthetase
Short name:
GluRS
Gene namesi
Name:gltX
Ordered Locus Names:SRU_1796
OrganismiSalinibacter ruber (strain DSM 13855 / M31)
Taxonomic identifieri309807 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidetes Order II. Incertae sedisRhodothermaceaeSalinibacter
ProteomesiUP000008674: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 488488Glutamate--tRNA ligaseUniRule annotationPRO_0000237398Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi309807.SRU_1796.

Structurei

3D structure databases

ProteinModelPortaliQ2S1L8.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi13 – 2311"HIGH" regionUniRule annotationAdd
BLAST
Motifi255 – 2595"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000252720.
KOiK01885.
OrthoDBiEOG6DRPF7.
PhylomeDBiQ2S1L8.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00022_B. Glu_tRNA_synth_B.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2S1L8-1 [UniParc]FASTAAdd to Basket

« Hide

MASDAPVRVR FAPSPTGRLH IGGLRTALYN YLFARKHDGD FVLRIEDTDQ    50
ARYEPGAEDD IREALAWTGL EHDEGPEQGG DYAPYRQSER SEHYHEYAQK 100
LVEAGRAYYA FDTEEELEEL REEHGAYDGS TRRQMRNSLT LSDEKVEQRI 150
DEGDDYVIRL KVPRQESVQV EDEIRGTVSF DTSEIDDQVL VKSDGMPTYH 200
LANIVDDHLM NISHVIRGEE WLSSTPKHVL MYDALGWEPP AFAHLPLILS 250
PNGGKLSKRD ANELGIPVYV MDYREAGYEP EALLNFLALL GWSPGTEEEL 300
FALDEMVETF SLDRVGASGV QFDLDKLRWV NEHYVRALSV DALAEKARPH 350
VEAAGYDVSD DRLQTICGLV QDRIQVVPEV VTDNRYFFED PEAYEEAGVE 400
KRWNEESADL LLAYADRLEG VDAFDTDTVE TELRDLADEK DVGAGAIIHP 450
SRLAVSGRSY GPGVFGLLAA VGKEACIRRM HRAVEALG 488
Length:488
Mass (Da):54,926
Last modified:May 30, 2006 - v2
Checksum:i08A6D9EF6C11EDA8
GO

Sequence cautioni

The sequence ABC45991.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000159 Genomic DNA. Translation: ABC45991.1. Different initiation.
RefSeqiYP_445913.1. NC_007677.1.

Genome annotation databases

EnsemblBacteriaiABC45991; ABC45991; SRU_1796.
GeneIDi3852853.
KEGGisru:SRU_1796.
PATRICi23426067. VBISalRub86502_1866.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000159 Genomic DNA. Translation: ABC45991.1 . Different initiation.
RefSeqi YP_445913.1. NC_007677.1.

3D structure databases

ProteinModelPortali Q2S1L8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 309807.SRU_1796.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC45991 ; ABC45991 ; SRU_1796 .
GeneIDi 3852853.
KEGGi sru:SRU_1796.
PATRICi 23426067. VBISalRub86502_1866.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000252720.
KOi K01885.
OrthoDBi EOG6DRPF7.
PhylomeDBi Q2S1L8.

Enzyme and pathway databases

BioCyci SRUB309807:GJJD-1794-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00022_B. Glu_tRNA_synth_B.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00464. gltX_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13855 / M31.

Entry informationi

Entry nameiSYE_SALRD
AccessioniPrimary (citable) accession number: Q2S1L8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: May 30, 2006
Last modified: May 14, 2014
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi