Q2S1K0 (Q2S1K0_SALRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	msrB HAMAP MF_01400 EMBL ABC46289.1
Ordered Locus Names:	SRU_1818

Organism

Salinibacter ruber (strain DSM 13855 / M31)

Taxonomic identifier

309807 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Salinibacter

Protein attributes

Sequence length	134 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP MF_01400 Zinc HAMAP MF_01400
Molecular function	Oxidoreductase HAMAP MF_01400 SAAS SAAS002579 EMBL ABC46289.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	122	1	Nucleophile By similarity HAMAP MF_01400
	Metal binding	50	1	Zinc By similarity HAMAP MF_01400
	Metal binding	53	1	Zinc By similarity HAMAP MF_01400
	Metal binding	99	1	Zinc By similarity HAMAP MF_01400
	Metal binding	102	1	Zinc By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	Q2S1K0 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 2BED58DAED503A8B	FASTA	134	14,928
	10 20 30 40 50 60 MAEIDSSRPS NDTLRDELTE EQYHVTQEAG TEKPFSGQYW DHKGDGLYRC VVCETPLFDS 70 80 90 100 110 120 DTKFESGSGW PSFYDVVEDG NVHLTSDHSL GMRRTEVVCD ECGAHLGHLF DDGPEPTGQR 130 YCINSAALAF DGDE

References

[1]

"The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea." Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H., Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K., Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L., Legault B., Rodriguez-Valera F. Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005) [PubMed: 16330755] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13855 / M31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000159 Genomic DNA. Translation: ABC46289.1.
RefSeq	YP_445931.1. NC_007677.1.
3D structure databases
ProteinModelPortal	Q2S1K0.
SMR	Q2S1K0. Positions 10-131.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2S1K0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3851210.
GenomeReviews	Gene locus SRU_1818 in contig CP000159_GR.
KEGG	sru:SRU_1818.
NMPDR	fig|309807.5.peg.1718.
PATRIC	23426113. VBISalRub86502_1885.
TIGR	SRU_1818.
Phylogenomic databases
eggNOG	COG0229.
HOGENOM	HBG715255.
OMA	LFESATK.
PhylomeDB	Q2S1K0.
ProtClustDB	CLSK2775302.
Enzyme and pathway databases
BioCyc	SRUB309807:SRU_1818-MONOMER.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2S1K0_SALRD

Accession

Primary (citable) accession number: Q2S1K0

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)