Q2S0T1 (Q2S0T1_SALRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862

Gene names

Name:	metF EMBL ABC44336.1
Ordered Locus Names:	SRU_2094

Organism

Salinibacter ruber (strain DSM 13855 / M31)

Taxonomic identifier

309807 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Salinibacter

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862
Cofactor	FAD By similarity. RuleBase RU003862
Sequence similarities	Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
Ligand	FAD RuleBase RU003862 Flavoprotein RuleBase RU003862
Molecular function	Oxidoreductase RuleBase RU003862
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	methylenetetrahydrofolate reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2S0T1 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 0691B98EE3983D64	FASTA	319	36,275
	10 20 30 40 50 60 MKVTEHFDRE SEPLISYEII PPKRGGSADQ ILGVVEELMP YEPPFIDVTS HSAEVEYKQK 70 80 90 100 110 120 DDGTWTRCVK RKRPGTIGLC AAIEARFDID TVPHILCKGF TREETEDALI ELNYLGVENV 130 140 150 160 170 180 LAIRGDDNGY EKSISGNRSR NEYAVDLVRQ IQDMNEGTYL EDLMDAEPTD FCVGVGGYPE 190 200 210 220 230 240 THFEAPNLAW DIMRLKEQVD AGADYIVTQM FFDNEYFFNF VDKCREVGIE VPIVPGLKIL 250 260 270 280 290 300 KRKRHLRLLP KYFHTEIPEE LAAEVDAADP DDVERIGVNW AIRQARELME AGVPGIHFYI 310 MSSADTVKKV VEPMHEEVA

References

[1]

"The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea." Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H., Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K., Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L., Legault B., Rodriguez-Valera F. Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005) [PubMed: 16330755] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13855 / M31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000159 Genomic DNA. Translation: ABC44336.1.
RefSeq	YP_446200.1. NC_007677.1.
3D structure databases
ProteinModelPortal	Q2S0T1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2S0T1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3852395.
GenomeReviews	Gene locus SRU_2094 in contig CP000159_GR.
KEGG	sru:SRU_2094.
NMPDR	fig|309807.5.peg.1980.
PATRIC	23426715. VBISalRub86502_2180.
TIGR	SRU_2094.
Phylogenomic databases
eggNOG	COG0685.
HOGENOM	HBG649727.
OMA	ITQMFFD.
PhylomeDB	Q2S0T1.
ProtClustDB	CLSK913627.
Enzyme and pathway databases
BioCyc	SRUB309807:SRU_2094-MONOMER.
Family and domain databases
InterPro	IPR003171. Mehydrof_redctse. IPR004620. MTHF_reductase_bac. [Graphical view]
KO	K00297.
Pfam	PF02219. MTHFR. 1 hit. [Graphical view]
TIGRFAMs	TIGR00676. Fadh2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2S0T1_SALRD

Accession

Primary (citable) accession number: Q2S0T1

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)