Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q2RZ44 (Q2RZ44_SALRD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ferrochelatase 2 HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase 2 HAMAP MF_00323
Protoheme ferro-lyase 2 HAMAP MF_00323
Gene names
Name:hemH EMBL ABC44798.1
Synonyms:hemH2 HAMAP MF_00323
Ordered Locus Names:SRU_2695
OrganismSalinibacter ruber (strain DSM 13855 / M31)
Taxonomic identifier309807 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Salinibacter

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2141Iron By similarity HAMAP MF_00323
Metal binding2941Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q2RZ44 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: BDA1F78CC13E4D9E

FASTA39444,363
        10         20         30         40         50         60 
MESGDTVGVV LLNLGGPDGE ESVEPFLYNL FMDPAIIDFS EVVYFQARGR VRQAFSKIIS 

        70         80         90        100        110        120 
YFRSQSVAED YKEISDDGGS PINPLTRDQA DNLEQTLNEQ YAAETGATFK TYMAMRYWEP 

       130        140        150        160        170        180 
FSEDAAAQMQ EDGVDKVVLL PLYPQYSKTT TGASLVYWHE LEKAGEIPAW PTTSVFEYAT 

       190        200        210        220        230        240 
YPKYIEALSD RIDEGLERFP DDVRDDVHLL FSAHGTPLSE MKDRDDPYCC LVHSTVKHLM 

       250        260        270        280        290        300 
EHRGFDHDFS TAFQSKVGPS EWLTPATDDT VEELAEEGED VLVIPVAFVT DHIETSYELA 

       310        320        330        340        350        360 
IEIPEDLEEE GAPIPEHYEV MPGLNSHPKF IETLADMTAA QLQLPNVQTP TPASERPCCQ 

       370        380        390 
VQDRDIRCHQ CQHVAEATDW SAPEEEQARE LETA

« Hide

References

[1]"The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea."
Mongodin E.F., Nelson K.E., Daugherty S., DeBoy R.T., Wister J., Khouri H., Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K., Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L., Legault B., Rodriguez-Valera F.
Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005) [PubMed: 16330755] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13855 / M31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000159 Genomic DNA. Translation: ABC44798.1.
RefSeqYP_446787.1. NC_007677.1.

3D structure databases

ProteinModelPortalQ2RZ44.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2RZ44.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3850957.
GenomeReviewsGene locus SRU_2695 in contig CP000159_GR.
KEGGsru:SRU_2695.
NMPDRfig|309807.5.peg.2546.
PATRIC23427981. VBISalRub86502_2803.
TIGRSRU_2695.

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMALQKPLAW.
PhylomeDBQ2RZ44.
ProtClustDBCLSK745540.

Enzyme and pathway databases

BioCycSRUB309807:SRU_2695-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2RZ44_SALRD
AccessionPrimary (citable) accession number: Q2RZ44
Entry history
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info