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Q2RYH3 (UPPP1_RHORT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 1

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 1
Undecaprenyl pyrophosphate phosphatase 1
Gene names
Name:uppP1
Ordered Locus Names:Rru_A0017
OrganismRhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) [Reference proteome] [HAMAP]
Taxonomic identifier269796 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 282282Undecaprenyl-diphosphatase 1 HAMAP-Rule MF_01006
PRO_0000250258

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane46 – 6621Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane117 – 13721Helical; Potential
Transmembrane150 – 17021Helical; Potential
Transmembrane193 – 21321Helical; Potential
Transmembrane226 – 24621Helical; Potential
Transmembrane260 – 28021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q2RYH3 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 629AEA2194B2B7AE

FASTA28229,284
        10         20         30         40         50         60 
MLLLQIVVLA LIQGITEVLP LSSTGHLALL PLLTPWPSPT TWPDQGVALD VAVHLGTLGA 

        70         80         90        100        110        120 
VALYFWRDEA AMIGGCLRLL KGKRDPGARL AFLVVLGTLP AVATVLLLAH FAGPIASPGL 

       130        140        150        160        170        180 
ATIGWTTLGF GLLLGVIDRL CMTVKRVEHM GGIDCLLIGL AQCLALLPGV SRTGVAMTAA 

       190        200        210        220        230        240 
RLLGYERVES ARFSMLLSIP AIAGAATLVG LDLARVGQSA MAPAALIAAV TAFLAAFLAV 

       250        260        270        280 
AAMMAWLRRH GFGPFVAYRV LLGAALLALA YLGPDLAPFL VS 

« Hide

References

[1]"Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C.
Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000230 Genomic DNA. Translation: ABC20822.1.
RefSeqYP_425109.1. NC_007643.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING269796.Rru_A0017.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC20822; ABC20822; Rru_A0017.
GeneID3833905.
KEGGrru:Rru_A0017.
PATRIC23323567. VBIRhoRub82919_0065.

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMARINCRIE.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycRRUB269796:GCN1-18-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP1_RHORT
AccessionPrimary (citable) accession number: Q2RYH3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: January 24, 2006
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families