Reviewed,
UniProtKB/Swiss-Prot Q2RYH3 (UPPP1_RHORT)
Last modified
January 19, 2010.
Version 32.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Undecaprenyl-diphosphatase 1 EC=3.6.1.27 Alternative name(s): Undecaprenyl pyrophosphate phosphatase 1 Bacitracin resistance protein 1 | ||||
| Gene names |
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| Organism | Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 269796 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Rhodospirillum |
Protein attributes
| Sequence length | 282 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP MF_01006 |
| Catalytic activity | Undecaprenyl diphosphate + H2O = undecaprenyl phosphate + phosphate. HAMAP MF_01006 |
| Subcellular location | Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_01006. |
| Miscellaneous | Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. HAMAP MF_01006 |
| Sequence similarities | Belongs to the uppP family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Antibiotic resistance Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis |
| Cellular component | Cell inner membrane Cell membrane Membrane |
| Domain | Transmembrane |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW dephosphorylationInferred from electronic annotation. Source: InterPro peptidoglycan biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW response to antibioticInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membraneInferred from electronic annotation. Source: HAMAP |
| Molecular function | undecaprenyl-diphosphatase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 282 | 282 | Undecaprenyl-diphosphatase 1 HAMAP MF_01006 | PRO_0000250258 | |||||
Regions | |||||||||
| Transmembrane | 1 – 21 | 21 | Potential | ||||||
| Transmembrane | 46 – 66 | 21 | Potential | ||||||
| Transmembrane | 91 – 111 | 21 | Potential | ||||||
| Transmembrane | 117 – 137 | 21 | Potential | ||||||
| Transmembrane | 150 – 170 | 21 | Potential | ||||||
| Transmembrane | 193 – 213 | 21 | Potential | ||||||
| Transmembrane | 226 – 246 | 21 | Potential | ||||||
| Transmembrane | 260 – 280 | 21 | Potential | ||||||
Sequences
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References
| [1] | "Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. Schwartz D.C.Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000230 Genomic DNA. Translation: ABC20822.1. |
| RefSeq | YP_425109.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q2RYH3. |
Genome annotation databases | |
| GeneID | 3833905. |
| GenomeReviews | Gene locus Rru_A0017 in contig CP000230_GR. |
| KEGG | rru:Rru_A0017. |
| NMPDR | fig|1085.1.peg.1097. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG1968. |
| HOGENOM | HBG391969. |
| OMA | AVSAYIC. |
Enzyme and pathway databases | |
| BioCyc | RRUB269796:RRU_A0017-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01006. Undec_diphosphatase. [Tree] |
| InterPro | IPR003824. Bacitracin-R_BacA. [Graphical view] |
| Pfam | PF02673. BacA. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | UPPP1_RHORT | ||||||||
| Accession | Primary (citable) accession number: Q2RYH3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

Clusters with


