Q2RWM4 (Q2RWM4_RHORT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase HAMAP-Rule MF_00230
Short name=NN:DBI PRT HAMAP-Rule MF_00230
EC=2.4.2.21 HAMAP-Rule MF_00230

Alternative name(s):
N(1)-alpha-phosphoribosyltransferase HAMAP-Rule MF_00230

Gene names

Name:	cobT HAMAP-Rule MF_00230
Ordered Locus Names:	Rru_A0667 EMBL ABC21471.1

Organism

Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) [Reference proteome] [HAMAP] EMBL ABC21471.1

Taxonomic identifier

269796 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Rhodospirillum › Rhodospirillum rubrum

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB) By similarity. HAMAP-Rule MF_00230 SAAS SAAS017846
Catalytic activity	Beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole = nicotinate + alpha-ribazole 5'-phosphate. HAMAP-Rule MF_00230 SAAS SAAS017846
Pathway	Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2. HAMAP-Rule MF_00230 SAAS SAAS017846
Sequence similarities	Belongs to the CobT family. HAMAP-Rule MF_00230

Ontologies

Keywords
Biological process	Cobalamin biosynthesis HAMAP-Rule MF_00230 SAAS SAAS017846
Molecular function	Glycosyltransferase HAMAP-Rule MF_00230 SAAS SAAS017846 EMBL ABC21471.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cobalamin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW nucleoside biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	cobalamin-transporting ATPase activity Inferred from electronic annotation. Source: HAMAP nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	302	1	Proton acceptor By similarity HAMAP-Rule MF_00230

Sequences

	Sequence		Length	Mass (Da)
	Q2RWM4 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 4DB7E87803E29AF5	FASTA	335	34,339
	10 20 30 40 50 60 MIQTLDDLRV LLGTLPGPDT VCRDIALARE PQLTKPRGAL GRIEQLAAFL SAWQGRHPPA 70 80 90 100 110 120 MQAPVAHVFA GNHGVAALGV SAFPPEVTLQ MVANYRKGGA AINQLCRAFG VRLGVTEIDL 130 140 150 160 170 180 DHPTKPFNQE PAMDEAEVVA ALNIGLGMDL AGADCLCLGE MGIANTTAAA AIALALYGGT 190 200 210 220 230 240 AEDWTGPGSG VSGSALDTKI KVVAEGAARH AKAGDGLEIL RRLGGRELAA IAGGIIAARL 250 260 270 280 290 300 ARVPVVLDGF IVCSAAACLK AVAADALDHC VLGHVSREPG HRRLVKALGL DPLLDIGMAL 310 320 330 GEATGAVTAV PLLKAACQCH MGMSTFAEAG VTDHD

References

[1]

"Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C. Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 11170 / NCIB 8255.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000230 Genomic DNA. Translation: ABC21471.1.
RefSeq	YP_425758.1. NC_007643.1.
3D structure databases
ProteinModelPortal	Q2RWM4.
ModBase	Search...
Protein-protein interaction databases
STRING	269796.Rru_A0667.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABC21471; ABC21471; Rru_A0667.
GeneID	3834305.
KEGG	rru:Rru_A0667.
PATRIC	23324915. VBIRhoRub82919_0724.
Phylogenomic databases
eggNOG	COG2038.
HOGENOM	HOG000263500.
KO	K00768.
OMA	FICSVAA.
Enzyme and pathway databases
UniPathway	UPA00061; UER00516.
Family and domain databases
Gene3D	1.10.1610.10. 1 hit.
HAMAP	MF_00230. CobT.
InterPro	IPR003200. Nict_dMeBzImd_PRibTrfase-like. IPR023195. Nict_dMeBzImd_PRibTrfase_N. IPR017846. Nict_dMeBzImd_PRibTrfase_pro. [Graphical view]
Pfam	PF02277. DBI_PRT. 1 hit. [Graphical view]
SUPFAM	SSF52733. NN:DBI_PRT. 1 hit.
TIGRFAMs	TIGR03160. cobT_DBIPRT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2RWM4_RHORT

Accession

Primary (citable) accession number: Q2RWM4

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)