ID   Q2RVH3_RHORT            Unreviewed;       680 AA.
AC   Q2RVH3;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABC21872.1};
GN   OrderedLocusNames=Rru_A1071 {ECO:0000313|EMBL:ABC21872.1};
OS   Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 /
OS   NCIMB 8255 / S1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Rhodospirillum.
OX   NCBI_TaxID=269796 {ECO:0000313|EMBL:ABC21872.1, ECO:0000313|Proteomes:UP000001929};
RN   [1] {ECO:0000313|EMBL:ABC21872.1, ECO:0000313|Proteomes:UP000001929}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1
RC   {ECO:0000313|Proteomes:UP000001929};
RX   PubMed=21886856; DOI=10.4056/sigs.1804360;
RA   Munk A.C., Copeland A., Lucas S., Lapidus A., Del Rio T.G., Barry K.,
RA   Detter J.C., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Kyrpides N.C.,
RA   Mavromatis K., Richardson P., Rohde M., Goker M., Klenk H.P., Zhang Y.,
RA   Roberts G.P., Reslewic S., Schwartz D.C.;
RT   "Complete genome sequence of Rhodospirillum rubrum type strain (S1).";
RL   Stand. Genomic Sci. 4:293-302(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000230; ABC21872.1; -; Genomic_DNA.
DR   RefSeq; WP_011388826.1; NC_007643.1.
DR   RefSeq; YP_426159.1; NC_007643.1.
DR   AlphaFoldDB; Q2RVH3; -.
DR   STRING; 269796.Rru_A1071; -.
DR   EnsemblBacteria; ABC21872; ABC21872; Rru_A1071.
DR   KEGG; rru:Rru_A1071; -.
DR   PATRIC; fig|269796.9.peg.1128; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_467559_0_0_5; -.
DR   Proteomes; UP000001929; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001929};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        117..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          493..607
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          81..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          205..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          656..680
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..253
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        257..335
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        658..674
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   680 AA;  73568 MW;  9E288863AE2AE15D CRC64;
     MASMTHYEVY LMELRGDWSL QQRYVSSERQ EAIDEAKRLE AELNLPTKVV RELFNPQSGM
     AEEQVVYISP KARELRERAM RRAGPHAAGG GPDSWVSSRG EKAKAKGKAP ATSLSDLMAR
     MILVVTASLI LAGIGGWLAP SLLSALSLTT GGGPASGNMR GVMVGVFLFL FTVSFLVIGR
     KLIPYAEILS RPKKTKPIEE AIGQRPDMAP GAHLAPPPKA ATSEEALSSI DPVALMEDMG
     PIPVPPPPTE PEQKIPAAQS RKARKKAAEA RAAEEEAERR RRENQDFQEH DAREMAAREK
     EKRAKEAEAR KAAEKEAEDK AAAEKEAEEK AAEQAKAAET LAAEDIASEP PASSPEQDRL
     RLTALSFLGE MVAALKVSHP QLDVYDRFGI NLFLAGACET LVAGNDLSGS AKPALLREML
     GVMGTRPALA LMFSDKLDEY LMEPRYMQML QAGRQAMGMK LAGGGEPFAP LPQLMADWRA
     PQAARPATAS TVAIVFTDMV GSTDINARFG DRHSHEITRV HNAIVRAALG RFDGREVKHT
     GDGIMATFPV VSQAVEAMIE VQKALAEHNR IAPDLRLDLR VGINAGEPLV DENDYHGLSV
     TLAARLCAQA QGGEVLCSGV VRDLAQGKDL TFRDRGQVML KGIGEPQRLF EAVWRDADAP
     SPPPPPPPPA EEPAAFKETP
//