Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chemotaxis response regulator protein-glutamate methylesterase 2

Gene

cheB2

Organism
Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR.UniRule annotation

Catalytic activityi

Protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei184UniRule annotation1
Active sitei210UniRule annotation1
Active sitei306UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processChemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis response regulator protein-glutamate methylesterase 2UniRule annotation (EC:3.1.1.61UniRule annotation)
Gene namesi
Name:cheB2UniRule annotation
Ordered Locus Names:Rru_A1406
OrganismiRhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Taxonomic identifieri269796 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum
Proteomesi
  • UP000001929 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002643121 – 363Chemotaxis response regulator protein-glutamate methylesterase 2Add BLAST363

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei574-aspartylphosphateUniRule annotation1

Post-translational modificationi

Phosphorylated by CheA. Phosphorylation suppresses the inhibitory activity of the N-terminal domain.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi269796.Rru_A1406.

Structurei

3D structure databases

ProteinModelPortaliQ2RUI8.
SMRiQ2RUI8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 123Response regulatoryPROSITE-ProRule annotationAdd BLAST118
Domaini172 – 363CheB-type methylesteraseUniRule annotationAdd BLAST192

Domaini

The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMP. Bacteria.
COG2201. LUCA.
HOGENOMiHOG000151424.
KOiK03412.
OMAiHAMAQTT.
OrthoDBiPOG091H045J.

Family and domain databases

CDDicd16432. CheB_Rec. 1 hit.
cd00156. REC. 1 hit.
Gene3Di3.40.50.180. 1 hit.
HAMAPiMF_00099. CheB_methylest. 1 hit.
InterProiView protein in InterPro
IPR035909. CheB_C.
IPR011006. CheY-like_superfamily.
IPR008248. Sig_transdc_resp-reg_CheB.
IPR000673. Sig_transdc_resp-reg_Me-estase.
IPR001789. Sig_transdc_resp-reg_receiver.
PfamiView protein in Pfam
PF01339. CheB_methylest. 1 hit.
PF00072. Response_reg. 1 hit.
PIRSFiPIRSF000876. RR_chemtxs_CheB. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF52738. SSF52738. 1 hit.
PROSITEiView protein in PROSITE
PS50122. CHEB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2RUI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRKIRVLIV DDSASVRQTM TEILESDPGI EVIGTAPDPY VAARRIQQEV
60 70 80 90 100
PDVITLDVEM PRMDGITFLR KIMAQRPIPV VVCSSLTETD SETASQAWEA
110 120 130 140 150
GAVEIILKPR VGTAQFLLES KIHICDVVKA AAGARLRSMP AAGRANRPRV
160 170 180 190 200
PEKKLTADAV LPPPVAGRNA MARTTESVIC IGASTGGTES LREVLEALPA
210 220 230 240 250
ASPAIVIVQH MPEKFTEAFA RRLDSLCDME VKEAVDGDTV MRGRVLIAPG
260 270 280 290 300
NHHMLLQRSG ARYYVSVKDG PLVSRHRPSV DVLFRSAASH AGSNAVGIIM
310 320 330 340 350
TGMGDDGARG LLEMRKAGAY TIAQDEATSV VFGMPKEAIA LGAADKILPL
360
EMLAMEILRA GNR
Length:363
Mass (Da):38,944
Last modified:January 24, 2006 - v1
Checksum:i6BD2BCB0C2FE4D05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000230 Genomic DNA. Translation: ABC22207.1.
RefSeqiWP_011389160.1. NC_007643.1.
YP_426494.1. NC_007643.1.

Genome annotation databases

EnsemblBacteriaiABC22207; ABC22207; Rru_A1406.
GeneIDi3834821.
KEGGirru:Rru_A1406.
PATRICifig|269796.9.peg.1476.

Similar proteinsi

Entry informationi

Entry nameiCHEB2_RHORT
AccessioniPrimary (citable) accession number: Q2RUI8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 24, 2006
Last modified: November 22, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome