Q2RTH6 (SURE_RHORT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	Rru_A1769

Organism

Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)

Taxonomic identifier

269796 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Rhodospirillum

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 261	261	5'-nucleotidase surE HAMAP MF_00060		PRO_0000235645
Sites
	Metal binding	18	1	Divalent metal cation By similarity
	Metal binding	19	1	Divalent metal cation By similarity
	Metal binding	50	1	Divalent metal cation By similarity
	Metal binding	102	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2RTH6 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: E162B51877039E04	FASTA	261	28,527
	10 20 30 40 50 60 MFSPLTDLSR ARILLSNDDG FEAEGLAVLE RVARTLSDDV WIVAPETEQS GAGHALTIHD 70 80 90 100 110 120 PLRFRARGEK RFSVRGTPTD CVLVAVNHLM DRPPDLVVSG INRGGNLGED VHYSGTVAAA 130 140 150 160 170 180 MEGTLLGLRA IALSQVFETN GTGIADPFQV AATHASDVIR RVCGRPWNRQ VLINVNFPDC 190 200 210 220 230 240 PLDAVTGIEL KRQGRRKMGD DIEERRDPRD RPYLWIGAQR KEDRKTAGTD MEAISRGAIT 250 260 VTPLCVDMTD LPTIEALTGA F

References

[1]

"Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C. Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 11170 / NCIB 8255.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000230 Genomic DNA. Translation: ABC22569.1.
RefSeq	YP_426856.1. NC_007643.1.
3D structure databases
ProteinModelPortal	Q2RTH6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2RTH6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3835191.
GenomeReviews	Gene locus Rru_A1769 in contig CP000230_GR.
KEGG	rru:Rru_A1769.
NMPDR	fig|1085.1.peg.2344.
PATRIC	23327196. VBIRhoRub82919_1847.
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	EVWTVAP.
PhylomeDB	Q2RTH6.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	RRUB269796:RRU_A1769-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_RHORT

Accession

Primary (citable) accession number: Q2RTH6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	January 24, 2006
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program