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Q2RTG6 (SYR_RHORT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Rru_A1779
OrganismRhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) [Reference proteome] [HAMAP]
Taxonomic identifier269796 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum

Protein attributes

Sequence length592 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 592592Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242082

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q2RTG6 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: C82325FE04D7C5A0

FASTA59263,983
        10         20         30         40         50         60 
MNVFHDIKET VLAQVAALQA EGRLPEGLET GRVAVEPPRE AAHGDMATNA AMVLAKPAGL 

        70         80         90        100        110        120 
APRAVAEMLV EKLVGVDGIV AAETAGPGFI NLRLDPKIWR KTLKTVLTLG TAFGASTMGR 

       130        140        150        160        170        180 
GAAVNVEFVS ANPTGPMHVG HGRGAVFGDA LAALLVKAGW AVTREYYVND AGAQVDSLAR 

       190        200        210        220        230        240 
ALYARYRVAV GDLDEAAFAA MLAAREIEYG GDYLVPVAAD IAQADGTRWT TVAESDWLPA 

       250        260        270        280        290        300 
FRAIGIERML ALIKEDLAAL GVVHDVFTSE QALVRAGRVD EMMTDLESRD LVYVGTLEPP 

       310        320        330        340        350        360 
KGKTPDDWEP RPQTLFRATG FGDEVDRPLK KSDGSWTYFA SDIAYHHDKF KRGFLGMINV 

       370        380        390        400        410        420 
LGADHGGYVK RLKAAVKAVS NGEAELDVKL VQLVKLLDNG EPVKMSKRAG TFITLREVVD 

       430        440        450        460        470        480 
EVGKDVVRFI MLTRKNDAAL DFDYARVTEK TRDNPVFYVQ YAHARACSVA RHAAQTFPGR 

       490        500        510        520        530        540 
DLSAAALAAT ADLDLLDADE EMAMVRLLAG WPRLVESAAE AHEPHRVAFY LGEVAAAFHG 

       550        560        570        580        590 
LWNRGNDNAE LRFLLPTDEA RSLARLALVQ AVASVIASGL EIFGVEPVKE MR 

« Hide

References

[1]"Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C.
Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000230 Genomic DNA. Translation: ABC22579.1.
RefSeqYP_426866.1. NC_007643.1.

3D structure databases

ProteinModelPortalQ2RTG6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING269796.Rru_A1779.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC22579; ABC22579; Rru_A1779.
GeneID3835201.
KEGGrru:Rru_A1779.
PATRIC23327216. VBIRhoRub82919_1857.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMARFIMLTR.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycRRUB269796:GCN1-1809-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_RHORT
AccessionPrimary (citable) accession number: Q2RTG6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: January 24, 2006
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries