ID   PNTAB_RHORT             Reviewed;         139 AA.
AC   Q2RSB3; Q59762; Q59764;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   16-JUN-2009, entry version 19.
DE   RecName: Full=NAD(P) transhydrogenase subunit alpha part 2;
DE            EC=1.6.1.2;
DE   AltName: Full=Nicotinamide nucleotide transhydrogenase subunit alpha 2;
DE   AltName: Full=Pyridine nucleotide transhydrogenase subunit alpha 2;
DE   AltName: Full=Proton-translocating transhydrogenase component 2;
DE   AltName: Full=dII;
GN   Name=pntAB; Synonyms=nntA2; OrderedLocusNames=Rru_A2182;
OS   Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Rhodospirillum.
OX   NCBI_TaxID=269796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=94356221; PubMed=8075801;
RA   Williams R., Cotton N.P., Thomas C.M., Jackson J.B.;
RT   "Cloning and sequencing of the genes for the proton-translocating
RT   nicotinamide nucleotide transhydrogenase from Rhodospirillum rubrum
RT   and the implications for the domain structure of the enzyme.";
RL   Microbiology 140:1595-1604(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G.,
RA   Reslewic S., Zhou S., Schwartz D.C.;
RT   "Complete sequence of the chromosome of Rhodospirillum rubrum ATCC
RT   11170.";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The transhydrogenation between NADH and NADP is coupled
CC       to respiration and ATP hydrolysis and functions as a proton pump
CC       across the membrane (By similarity).
CC   -!- CATALYTIC ACTIVITY: NADPH + NAD(+) = NADP(+) + NADH.
CC   -!- SUBUNIT: Complex of an alpha and a beta chain; in Rhodospirillum,
CC       the alpha chain seems to be made of two subunits (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (By similarity).
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DR   EMBL; U05294; AAA62494.1; -; Genomic_DNA.
DR   EMBL; CP000230; ABC22982.1; -; Genomic_DNA.
DR   RefSeq; YP_427269.1; -.
DR   GeneID; 3835609; -.
DR   GenomeReviews; CP000230_GR; Rru_A2182.
DR   KEGG; rru:Rru_A2182; -.
DR   NMPDR; fig|1085.1.peg.3657; -.
DR   HOGENOM; Q2RSB3; -.
DR   OMA; Q2RSB3; LALQASH.
DR   BioCyc; RRUB269796:RRU_A2182-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008750; F:NAD(P)+ transhydrogenase (AB-specific) acti...; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane; NAD;
KW   NADP; Oxidoreductase; Transmembrane.
FT   CHAIN         1    139       NAD(P) transhydrogenase subunit alpha
FT                                part 2.
FT                                /FTId=PRO_0000231664.
FT   TRANSMEM     49     69       Potential.
FT   TRANSMEM     78     98       Potential.
FT   TRANSMEM    107    127       Potential.
SQ   SEQUENCE   139 AA;  14889 MW;  04742D87817A8879 CRC64;
     MEDKNILVEG FNQLSQQALE LSQHAQALAL QASHAVLPAA AATEGASEFW WLMTVFVLAC
     FIGFYVVWSV TPALHSPLMG VTNAISSVIV VGALIATGPE AFSASKVLGF FAILLASVNI
     FGGFIVTQRM LAMFKKKQK
//