Reviewed, UniProtKB/Swiss-Prot Q2RPW9 (GPH_RHORT)

Names and origin

Protein names

Recommended name:
    Phosphoglycolate phosphatase
      Short name=PGPase
      Short name=PGP
    EC=3.1.3.18

Gene names

Name:	cbbZ
Ordered Locus Names:	Rru_A3031

Organism

Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) [Complete proteome] [HAMAP]

Taxonomic identifier

269796 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Rhodospirillum

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress By similarity.
Catalytic activity	2-phosphoglycolate + H2O = glycolate + phosphate. HAMAP MF_00495
Pathway	Organic acid metabolism; glycolic acid biosynthesis; glycolic acid from 2-phosphoglycolic acid: step 1/1. HAMAP MF_00495
Sequence similarities	Belongs to the HAD-like hydrolase superfamily. CbbY/cbbZ/gph/yieH family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism Photosynthesis
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphoglycolate phosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Phosphoglycolate phosphatase HAMAP MF_00495		PRO_0000238174
Sites
	Active site	8	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2RPW9-1 [UniParc]. Last modified May 30, 2006. Version 2. Checksum: 7D4F0C118BFBEA59	FASTA	241	24,507
	10 20 30 40 50 60 MPKAVIFDLD GTLVHSLPGL TDALNKTLAE DDLAPLDEAA VKRMVGEGAG LLVARAFAAY 70 80 90 100 110 120 GLGRADDADD TATQARLARF LAHYAPDPLA GASVYPGALA LLGALAARGI RLGVCTNKPE 130 140 150 160 170 180 GPARALLEGL GLADPIMDVV GGDTLAQRKP DPAPLRALLD SLGVEADQAL MVGDSPTDVA 190 200 210 220 230 240 TAKAAGVPVV VMSYGYSREP VASLGALAVF DDFASLGDWL GFPQPGGDRL GATPALSENP A

References

[1]

"Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C. Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000230 Genomic DNA. Translation: ABC23826.1. Different initiation.
RefSeq	YP_428113.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3836476.
GenomeReviews	Gene locus Rru_A3031 in contig CP000230_GR.
KEGG	rru:Rru_A3031.
NMPDR	fig|1085.1.peg.672.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2RPW9.
Enzyme and pathway databases
BioCyc	RRUB269796:RRU_A3031-MON.
Family and domain databases
HAMAP	MF_00495. [Tree]
InterPro	IPR005834. Dehalogen-like_hydro. IPR006439. HAD-SF_hydro_IA_v1. IPR006402. HAD-SF_hydro_IA_v3. IPR005833. Haloacid_DH/epoxide_hydro. IPR006346. PGP_bact. [Graphical view]
Pfam	PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00413. HADHALOGNASE.
TIGRFAMs	TIGR01549. HAD-SF-IA-v1. 1 hit. TIGR01509. HAD-SF-IA-v3. 1 hit. TIGR01449. PGP_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GPH_RHORT

Accession

Primary (citable) accession number: Q2RPW9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	May 30, 2006
Last modified:	June 16, 2009
This is version 26 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)