Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2RPV1

- GCSPA_RHORT

UniProt

Q2RPV1 - GCSPA_RHORT

Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene

gcvPA

Organism
Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (24 Jan 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.UniRule annotation

    Catalytic activityi

    Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

    GO - Molecular functioni

    1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glycine catabolic process Source: InterPro
    2. nucleoside metabolic process Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciRRUB269796:GCN1-3103-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotation (EC:1.4.4.2UniRule annotation)
    Alternative name(s):
    Glycine cleavage system P-protein subunit 1UniRule annotation
    Glycine decarboxylase subunit 1UniRule annotation
    Glycine dehydrogenase (aminomethyl-transferring) subunit 1UniRule annotation
    Gene namesi
    Name:gcvPAUniRule annotation
    Ordered Locus Names:Rru_A3049
    OrganismiRhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
    Taxonomic identifieri269796 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum
    ProteomesiUP000001929: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 448448Probable glycine dehydrogenase (decarboxylating) subunit 1PRO_1000045675Add
    BLAST

    Interactioni

    Subunit structurei

    The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi269796.Rru_A3049.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2RPV1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GcvP family. N-terminal subunit subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0403.
    HOGENOMiHOG000132025.
    KOiK00282.
    OMAiFFHEAVL.
    OrthoDBiEOG6XWV3B.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    HAMAPiMF_00712. GcvPA.
    InterProiIPR023010. GcvPA.
    IPR020580. GDC-P_N.
    IPR020581. GDC_P.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11773. PTHR11773. 1 hit.
    PfamiPF02347. GDC-P. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006815. GcvPA. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2RPV1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRYLPHSEAD RAAMLATIGA ASVEDLFRDV PREALDQAAF DALPDHGGEM    50
    EVERALSALA ARNLTAGSVP CFLGAGSYRH HVPAAVDALI QRGEFLTSYT 100
    PYQAEVSQGT LQYLFEFQTQ VALITGMEVA NASMYDGATA CAEAAAMAVR 150
    ITRRRKVLMA GGLHPHYTAT TQTLLACLGH EGEGLPPDPL ALGDLIGRVG 200
    SDTACVIVQN PDFFGRLRDL SPLAEACHAA GALLVVAVCE PVSLGLVAPP 250
    GAMGADIVVA EGHALGSPTG FGGPGVGLFA TREKYLRQMP GRLAGETLDE 300
    SGKRGYVLTL STREQHIRRE KATSNICTNS GLIALAFTIH MTLLGEAGFT 350
    RLAWINHANA VALAEKLARV KGVKVLPETF FNEFTLRLPK PAAEVVEALA 400
    ARSILAGVPV SRFLPTYPEL ANLLLVNATE LTTPEDADAL VAALKEVL 448
    Length:448
    Mass (Da):47,384
    Last modified:January 24, 2006 - v1
    Checksum:i92B0C9703B92C335
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000230 Genomic DNA. Translation: ABC23844.1.
    RefSeqiWP_011390797.1. NC_007643.1.
    YP_428131.1. NC_007643.1.

    Genome annotation databases

    EnsemblBacteriaiABC23844; ABC23844; Rru_A3049.
    GeneIDi3836495.
    KEGGirru:Rru_A3049.
    PATRICi23329864. VBIRhoRub82919_3159.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000230 Genomic DNA. Translation: ABC23844.1 .
    RefSeqi WP_011390797.1. NC_007643.1.
    YP_428131.1. NC_007643.1.

    3D structure databases

    ProteinModelPortali Q2RPV1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 269796.Rru_A3049.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC23844 ; ABC23844 ; Rru_A3049 .
    GeneIDi 3836495.
    KEGGi rru:Rru_A3049.
    PATRICi 23329864. VBIRhoRub82919_3159.

    Phylogenomic databases

    eggNOGi COG0403.
    HOGENOMi HOG000132025.
    KOi K00282.
    OMAi FFHEAVL.
    OrthoDBi EOG6XWV3B.

    Enzyme and pathway databases

    BioCyci RRUB269796:GCN1-3103-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    HAMAPi MF_00712. GcvPA.
    InterProi IPR023010. GcvPA.
    IPR020580. GDC-P_N.
    IPR020581. GDC_P.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11773. PTHR11773. 1 hit.
    Pfami PF02347. GDC-P. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006815. GcvPA. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
      , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C.
      Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S.1.

    Entry informationi

    Entry nameiGCSPA_RHORT
    AccessioniPrimary (citable) accession number: Q2RPV1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: January 24, 2006
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3