Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi678 – 6858ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRRUB269796:GCN1-3604-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutSUniRule annotation
Gene namesi
Name:mutSUniRule annotation
Ordered Locus Names:Rru_A3541
OrganismiRhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Taxonomic identifieri269796 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum
Proteomesi
  • UP000001929 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 929929DNA mismatch repair protein MutSPRO_0000335217Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi269796.Rru_A3541.

Structurei

3D structure databases

ProteinModelPortaliQ2RNG0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DNA mismatch repair MutS family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D86. Bacteria.
COG0249. LUCA.
HOGENOMiHOG000221407.
KOiK03555.
OMAiCLLLFRM.
OrthoDBiPOG091H0293.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS. 1 hit.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2RNG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFFADRSPF VRPLSGYAPV TPAAPRSTGS AAAPPPSPAV LDDRSGTEGD
60 70 80 90 100
VTPMMAQYLA VKAAHPDCLL FYRMGDFYEM FFEDAVKAAE TLDIALTKRG
110 120 130 140 150
RHAGADIPMC GVPIHSHEGY LSRLIRAGIK VAICEQMEDP AEARRQRGYK
160 170 180 190 200
AVVRRDVIRV VTAGTLTEDE LLDARAHNYL AAVVRLRDAV GMAWVDVSTG
210 220 230 240 250
DLVAQPLAEA DIGPALARLA PGEVLMPEKL AGDPALREIL APLAGRISPL
260 270 280 290 300
PASRFDSENA RKRVEGLFGV KALDGFGGFG RAEVAAIGAL IDYVELTQVG
310 320 330 340 350
RLPRLSPPRR LSLGAILEID GATRRNLELT ETLGGGRKGS LLARIDCTVT
360 370 380 390 400
GAGARLLAER LAAPLTDPAQ IGARLDGVGF LVSAERVRGD LRDTLRGCPD
410 420 430 440 450
IARALSRLSL GRGGPRDLAA IGEALSRIPA LRVLVVGAGL GEPPTELTAA
460 470 480 490 500
LIDLGSHEGL VDLLGRALDA DLPLLARDGG FIRPGYDAGL DELRALRDEG
510 520 530 540 550
RRLIAGLQAR YASETAIPAL KIKHNNVLGY FIEVAAGRAD KLMAAGGPFL
560 570 580 590 600
HRQTLASQVR FTTVELSELE DKIRGAADKA LALEQALFAT LCAEVLGCAA
610 620 630 640 650
DIARAANGLA CLDVAAALAD LAARERYARP VVDNSTAFRI HKGRHPVVEA
660 670 680 690 700
ALADQAGPAF VANDCDLAPD QRLWLLTGPN MAGKSTFLRQ NALIAVLAQM
710 720 730 740 750
GSFVPAESAE IGVIDRLFSR VGAADDLARG RSTFMVEMVE TAAILNQATE
760 770 780 790 800
RSLVILDEIG RGTATYDGLS IAWATVESLH DATRCRALFA THYHELTALA
810 820 830 840 850
SRLDRLSCHT LRIKEWKDQV VFLHEVGPGA ADRSYGIHVA KLAGLPAAVI
860 870 880 890 900
ARAEQVLAIL EKGDASSAAT RLADDLPLFA AARPRAGLPT PPPGPHPLAE
910 920
ALNAINPDEM TPREALDALY RLKAVMKRE
Length:929
Mass (Da):98,820
Last modified:January 24, 2006 - v1
Checksum:iF934132105EA8BC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000230 Genomic DNA. Translation: ABC24335.1.
RefSeqiWP_011391288.1. NC_007643.1.
YP_428622.1. NC_007643.1.

Genome annotation databases

EnsemblBacteriaiABC24335; ABC24335; Rru_A3541.
GeneIDi3836996.
KEGGirru:Rru_A3541.
PATRICi23330880. VBIRhoRub82919_3658.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000230 Genomic DNA. Translation: ABC24335.1.
RefSeqiWP_011391288.1. NC_007643.1.
YP_428622.1. NC_007643.1.

3D structure databases

ProteinModelPortaliQ2RNG0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269796.Rru_A3541.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC24335; ABC24335; Rru_A3541.
GeneIDi3836996.
KEGGirru:Rru_A3541.
PATRICi23330880. VBIRhoRub82919_3658.

Phylogenomic databases

eggNOGiENOG4105D86. Bacteria.
COG0249. LUCA.
HOGENOMiHOG000221407.
KOiK03555.
OMAiCLLLFRM.
OrthoDBiPOG091H0293.

Enzyme and pathway databases

BioCyciRRUB269796:GCN1-3604-MONOMER.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS. 1 hit.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMUTS_RHORT
AccessioniPrimary (citable) accession number: Q2RNG0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: January 24, 2006
Last modified: September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.