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Q2RMW0 (AROB_RHORT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:Rru_A3741
OrganismRhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
Taxonomic identifier269796 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Rhodospirillum

Protein attributes

Sequence length385 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3853853-dehydroquinate synthase HAMAP MF_00110
PRO_0000231122

Sequences

Sequence LengthMass (Da)Tools
Q2RMW0 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 56FC30C6C0C784C5

FASTA38540,260
        10         20         30         40         50         60 
MSPDTAADAA ADPALQSSVL TVSLGERSYP IHIGPGLLGR AGALIAPLLR KPRVFVVTDA 

        70         80         90        100        110        120 
TVAALHLDPL LASLGAAGIA HDHVVLPAGE ATKSFSQLEE LLDLLLAARF ERSTTLLALG 

       130        140        150        160        170        180 
GGVIGDLVGF AAAILLRGVD FIQIPTTLLA QVDSSVGGKT GINTAYGKNL VGAFHQPRLV 

       190        200        210        220        230        240 
LADTTVLDTL PRRELLAGYG EVVKYGVIDD PAFFDWLEEH GSALIAGDGG ARIHAVLTAC 

       250        260        270        280        290        300 
RAKARVVAED EREGGRRALL NLGHTFGHAL EAETGFGPTL LHGEAVALGM VMALDLSVRL 

       310        320        330        340        350        360 
GLCPPADAAR LRAHLDHVGL PTDPRRLEGA PAWNAERLLA AMDHDKKVED GKVTFVLARG 

       370        380 
IGRSLLWREA DTASVLATLR AAVAP

« Hide

References

[1]"Complete sequence of the chromosome of Rhodospirillum rubrum ATCC 11170."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Mavrommatis K., Richardson P., Zhang Y., Roberts G., Reslewic S., Zhou S., Schwartz D.C.
Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11170 / NCIB 8255.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000230 Genomic DNA. Translation: ABC24535.1.
RefSeqYP_428822.1. NC_007643.1.

3D structure databases

ProteinModelPortalQ2RMW0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2RMW0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3837198.
GenomeReviewsGene locus Rru_A3741 in contig CP000230_GR.
KEGGrru:Rru_A3741.
NMPDRfig|1085.1.peg.1173.
PATRIC23331300. VBIRhoRub82919_3866.

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAMADEHEQ.
PhylomeDBQ2RMW0.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycRRUB269796:RRU_A3741-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_RHORT
AccessionPrimary (citable) accession number: Q2RMW0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: January 24, 2006
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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