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Protein

Protein-arginine kinase

Gene

mcsB

Organism
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the specific phosphorylation of arginine residues in proteins.UniRule annotation

Catalytic activityi

ATP + a [protein]-L-arginine = ADP + a [protein]-N(omega)-phospho-L-arginine.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei90ATPUniRule annotation1
Binding sitei124ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28ATPUniRule annotation5
Nucleotide bindingi175 – 179ATPUniRule annotation5
Nucleotide bindingi206 – 211ATPUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-arginine kinaseUniRule annotation (EC:2.7.14.1UniRule annotation)
Gene namesi
Name:mcsBUniRule annotation
Ordered Locus Names:Moth_0161
OrganismiMoorella thermoacetica (strain ATCC 39073 / JCM 9320)
Taxonomic identifieri264732 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeMoorella groupMoorella
Proteomesi
  • UP000007053 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000612651 – 350Protein-arginine kinaseAdd BLAST350

Interactioni

Protein-protein interaction databases

STRINGi264732.Moth_0161.

Structurei

3D structure databases

ProteinModelPortaliQ2RM40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 253Phosphagen kinase C-terminalUniRule annotationAdd BLAST233

Sequence similaritiesi

Belongs to the ATP:guanido phosphotransferase family.UniRule annotation
Contains 1 phosphagen kinase C-terminal domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG41066A3. Bacteria.
COG3869. LUCA.
HOGENOMiHOG000082112.
KOiK19405.
OMAiRIQCILP.
OrthoDBiPOG091H027W.

Family and domain databases

CDDicd07930. bacterial_phosphagen_kinase. 1 hit.
Gene3Di3.30.590.10. 1 hit.
HAMAPiMF_00602. Prot_Arg_kinase. 1 hit.
InterProiIPR023660. Arg_Kinase.
IPR000749. ATP-guanido_PTrfase.
IPR022415. ATP-guanido_PTrfase_AS.
IPR022414. ATP-guanido_PTrfase_cat.
IPR014746. Gln_synth/guanido_kin_cat_dom.
[Graphical view]
PANTHERiPTHR11547. PTHR11547. 2 hits.
PfamiPF00217. ATP-gua_Ptrans. 1 hit.
[Graphical view]
PROSITEiPS00112. PHOSPHAGEN_KINASE. 1 hit.
PS51510. PHOSPHAGEN_KINASE_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2RM40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLNLERNSK WMEGSGPQAD IVISSRIRLA RNLKGLPFPN LMNSDQQARV
60 70 80 90 100
VSQVSRAIQA PMVFQAVGEL KLQPLRELAP VERQILVEKH LISPDLAAGG
110 120 130 140 150
GEKAVVLRDD EAVSIMVNEE DHLRLQCLLP AMMLHEAWRL ADAADDALEN
160 170 180 190 200
ELDFAFDQER GYLTACPTNV GTGLRASTML HLPALVLTRQ AGPVLSALTK
210 220 230 240 250
VGVAVRGLYG EGTEAQGNIF QVSNQITLGR SEEEIINNLS AVTVRLADQE
260 270 280 290 300
REARELLRRQ SRWQLEDRVG RAYGVLTNAR ILSSQEALQL LSDVRLGAEM
310 320 330 340 350
KIIRGLDQRL LNQLMVRIQP AFLQFSAGKE MTPMERDVHR AAMVRELLAG
Length:350
Mass (Da):38,809
Last modified:January 24, 2006 - v1
Checksum:i2106B9BABD79CF3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000232 Genomic DNA. Translation: ABC18499.1.
RefSeqiWP_011391708.1. NC_007644.1.
YP_429042.1. NC_007644.1.

Genome annotation databases

EnsemblBacteriaiABC18499; ABC18499; Moth_0161.
GeneIDi3831873.
KEGGimta:Moth_0161.
PATRICi22637343. VBIMooThe6753_0172.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000232 Genomic DNA. Translation: ABC18499.1.
RefSeqiWP_011391708.1. NC_007644.1.
YP_429042.1. NC_007644.1.

3D structure databases

ProteinModelPortaliQ2RM40.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264732.Moth_0161.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC18499; ABC18499; Moth_0161.
GeneIDi3831873.
KEGGimta:Moth_0161.
PATRICi22637343. VBIMooThe6753_0172.

Phylogenomic databases

eggNOGiENOG41066A3. Bacteria.
COG3869. LUCA.
HOGENOMiHOG000082112.
KOiK19405.
OMAiRIQCILP.
OrthoDBiPOG091H027W.

Family and domain databases

CDDicd07930. bacterial_phosphagen_kinase. 1 hit.
Gene3Di3.30.590.10. 1 hit.
HAMAPiMF_00602. Prot_Arg_kinase. 1 hit.
InterProiIPR023660. Arg_Kinase.
IPR000749. ATP-guanido_PTrfase.
IPR022415. ATP-guanido_PTrfase_AS.
IPR022414. ATP-guanido_PTrfase_cat.
IPR014746. Gln_synth/guanido_kin_cat_dom.
[Graphical view]
PANTHERiPTHR11547. PTHR11547. 2 hits.
PfamiPF00217. ATP-gua_Ptrans. 1 hit.
[Graphical view]
PROSITEiPS00112. PHOSPHAGEN_KINASE. 1 hit.
PS51510. PHOSPHAGEN_KINASE_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMCSB_MOOTA
AccessioniPrimary (citable) accession number: Q2RM40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: January 24, 2006
Last modified: November 2, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.