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Protein

Adenine deaminase

Gene

ade

Organism
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Moth_0463
OrganismiMoorella thermoacetica (strain ATCC 39073 / JCM 9320)
Taxonomic identifieri264732 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeMoorella groupMoorella
Proteomesi
  • UP000007053 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002923881 – 596Adenine deaminaseAdd BLAST596

Interactioni

Protein-protein interaction databases

STRINGi264732.Moth_0463.

Structurei

3D structure databases

ProteinModelPortaliQ2RL95.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiPOG091H00I8.

Family and domain databases

CDDicd01295. AdeC. 1 hit.
Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2RL95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPTRRPLAE VTRELVAVAT GKLPADTVIK GGKVVNVFTG EILPWDIAIK
60 70 80 90 100
NGRIASVGDV SAAVGPETEV IDASGYYLCP GFMDGHVHVE SSMVTVTQFA
110 120 130 140 150
RAVLPGGTTA IFMDPHEIAN VLGMDGVKLM VDEGRELPLK VFATMPSCVP
160 170 180 190 200
AAPGFEDAGA SFGPEEVAAA MQWPGICGLG EMMNFPGVLA GDPAVHGELR
210 220 230 240 250
ATLAAGKPIT GHFAMPADFQ GLAGYTAAGI SSCHESTRTE DALNRLRLGM
260 270 280 290 300
YAMMREGSAW HDIKATIKSL TETRVDSRRA MLVSDDTHPE TLLSTGHLNH
310 320 330 340 350
VVRRAIEEGL NPIRAIQAVT INTAECFGVA QDLGAIAPGR YADILFLKDL
360 370 380 390 400
ARVAIDKVMV DGRVVAAGGR LLVDLPAVAY PDRVRHSVHL KEPLTPWHFR
410 420 430 440 450
INAPAGKSRV QVRVMEIIEA NVNTRHLTVT VPVVDGQVTA GVEADLAKVA
460 470 480 490 500
VVERHGGNGS IGLGFVRGFG FKAGAVASTV AHDSHNLLIV GMNDADMALA
510 520 530 540 550
GNTLAGCGGG MVAVRDGQVL ALLPLPIAGL MSDRPVEEVA ARLAAVHRAW
560 570 580 590
QELGCRLVSP FMTMALLSLP VLPELRLTNR GLVDTLQFKM VDLITG
Length:596
Mass (Da):63,030
Last modified:January 24, 2006 - v1
Checksum:iBF57381721AAD503
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000232 Genomic DNA. Translation: ABC18794.1.
RefSeqiWP_011392001.1. NC_007644.1.
YP_429337.1. NC_007644.1.

Genome annotation databases

EnsemblBacteriaiABC18794; ABC18794; Moth_0463.
GeneIDi3830892.
KEGGimta:Moth_0463.
PATRICi22638001. VBIMooThe6753_0498.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000232 Genomic DNA. Translation: ABC18794.1.
RefSeqiWP_011392001.1. NC_007644.1.
YP_429337.1. NC_007644.1.

3D structure databases

ProteinModelPortaliQ2RL95.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264732.Moth_0463.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC18794; ABC18794; Moth_0463.
GeneIDi3830892.
KEGGimta:Moth_0463.
PATRICi22638001. VBIMooThe6753_0498.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiPOG091H00I8.

Family and domain databases

CDDicd01295. AdeC. 1 hit.
Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADEC_MOOTA
AccessioniPrimary (citable) accession number: Q2RL95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: November 2, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.