ID   IDI2_MOOTA              Reviewed;         346 AA.
AC   Q2RIU8;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Isopentenyl-diphosphate delta-isomerase;
DE            Short=IPP isomerase;
DE            EC=5.3.3.2;
DE   AltName: Full=Isopentenyl pyrophosphate isomerase;
GN   Name=fni; OrderedLocusNames=Moth_1328;
OS   Moorella thermoacetica (strain ATCC 39073).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteriaceae; Moorella group; Moorella.
OX   NCBI_TaxID=264732;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18631365; DOI=10.1111/j.1462-2920.2008.01679.x;
RA   Pierce E., Xie G., Barabote R.D., Saunders E., Han C.S., Detter J.C.,
RA   Richardson P., Brettin T.S., Das A., Ljungdahl L.G., Ragsdale S.W.;
RT   "The complete genome sequence of Moorella thermoacetica (f.
RT   Clostridium thermoaceticum).";
RL   Environ. Microbiol. 10:2550-2573(2008).
CC   -!- FUNCTION: Catalyzes the 1,3-allylic rearrangement of the
CC       homoallylic substrate isopentenyl (IPP) to its allylic isomer,
CC       dimethylallyl diphosphate (DMAPP) (By similarity).
CC   -!- CATALYTIC ACTIVITY: Isopentenyl diphosphate = dimethylallyl
CC       diphosphate.
CC   -!- COFACTOR: FMN (By similarity).
CC   -!- COFACTOR: NADPH (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the IPP isomerase type 2 family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000232; ABC19641.1; -; Genomic_DNA.
DR   RefSeq; YP_430184.1; -.
DR   GeneID; 3831038; -.
DR   GenomeReviews; CP000232_GR; Moth_1328.
DR   KEGG; mta:Moth_1328; -.
DR   NMPDR; fig|264732.9.peg.1323; -.
DR   HOGENOM; Q2RIU8; -.
DR   OMA; Q2RIU8; AMGVGSQ.
DR   BioCyc; MTHE264732:MOTH_1328-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase act...; IEA:HAMAP.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00354; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR011179; IPdP_isomerase.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   PANTHER; PTHR10578:SF3; IPdP_isomerase; 1.
DR   PIRSF; PIRSF003314; IPP_isomerase; 1.
DR   TIGRFAMs; TIGR02151; IPP_isom_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Flavoprotein; FMN; Isomerase;
KW   Isoprene biosynthesis; NADP.
FT   CHAIN         1    346       Isopentenyl-diphosphate delta-isomerase.
FT                                /FTId=PRO_0000229505.
SQ   SEQUENCE   346 AA;  37305 MW;  5730A1FD40989742 CRC64;
     MNEREYIGRG RRKLEHLRFF QEDSKGSNGL EDVHLVHQAL PELNWSDIDL TCRWLGKTLA
     APFIINALTG GPPETLAINA ALARVARRTG IALAVGSQRA GLENKEWRES FTIVRRENAN
     GLILANIGAG NSPADAGEAV AMIAADGLQV HLNAAQELIM PEGDRAFRGW LENIRGMVNT
     LGVPVIAKEV GFGLSRETAL QLYQAGVRIM DVGGRGGTNF AAIEERRRGR SVAALAGWGL
     STAVSILEIR ELGLPVEVVA TGGIRSALDA ARALALGAKI VGAAGYFLKI LLEQGEDALT
     EEILQWQEDL KRICLLTGCT TPAELATKPV VITGQTRAWL EGRQRH
//