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Q2RGI3 (Q2RGI3_MOOTA) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201
EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:Moth_2167
OrganismMoorella thermoacetica (strain ATCC 39073) [Reference proteome] [HAMAP] EMBL ABC20456.1
Taxonomic identifier264732 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteraceae › Moorella group › Moorella ›

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU000608 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 RuleBase RU000608 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site361Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2641Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1341Substrate By similarity HAMAP-Rule MF_01201
Binding site3121Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue361N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q2RGI3 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 12928995A137174E

FASTA37340,361
        10         20         30         40         50         60 
MSRPVWAEID LEAVARNVRA IKKILAPQTE IMAIVKANAY GHGAGPVART ALANGVSWLG 

        70         80         90        100        110        120 
VATLGEALDL RREGITAPLL ILGYTPPEDA GRVVEADISQ TVFSVDQARA LNAAAAAVGT 

       130        140        150        160        170        180 
RARLHLKIDT GMGRLGFLPR EAVTAARAIA DLPHVTLEGI FTHFAASDAA DKTYTQRQLG 

       190        200        210        220        230        240 
LFQQVIAELE KQGITFPWRH AANSGAIIDL PGTHFNLVRA GIILYGHYPS PEVQRKRLAL 

       250        260        270        280        290        300 
TPVMTLKTRV VLVKEVPAGS YISYGCTYRT PGPARIATLP VGYADGYSRL LSNRAEVLVR 

       310        320        330        340        350        360 
GRRAPIVGRI CMDQCMIDVT AIPEVRVGDE VVLFGRQGGQ TLTVEEVAAW MGTINYEILC 

       370 
LISKRVPRVY LHS

« Hide

References

[1]"The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum)."
Pierce E., Xie G., Barabote R.D., Saunders E., Han C.S., Detter J.C., Richardson P., Brettin T.S., Das A., Ljungdahl L.G., Ragsdale S.W.
Environ. Microbiol. 10:2550-2573(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 39073.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000232 Genomic DNA. Translation: ABC20456.1.
RefSeqYP_430999.1. NC_007644.1.

3D structure databases

ProteinModelPortalQ2RGI3.
ModBaseSearch...

Protein-protein interaction databases

STRING264732.Moth_2167.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC20456; ABC20456; Moth_2167.
GeneID3833016.
KEGGmta:Moth_2167.
PATRIC22641786. VBIMooThe6753_2361.

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAEGMYTHF.
ProtClustDBCLSK843233.

Enzyme and pathway databases

BioCycMTHE264732:GH0A-2246-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2RGI3_MOOTA
AccessionPrimary (citable) accession number: Q2RGI3
Entry history
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: May 29, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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