Q2RFT7 (Q2RFT7_MOOTA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thioredoxin reductase RuleBase RU003881
EC=1.8.1.9 RuleBase RU003881

Gene names

Ordered Locus Names:

Moth_2420

Organism

Moorella thermoacetica (strain ATCC 39073)

Taxonomic identifier

264732 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacteriaceae › Moorella group › Moorella

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003881
Sequence similarities	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003880

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003880
Ligand	FAD RuleBase RU003880 Flavoprotein RuleBase RU003880
Molecular function	Oxidoreductase RuleBase RU003880
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2RFT7 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 6FA673A89EDDA246	FASTA	304	32,331
	10 20 30 40 50 60 MVYDLMIIGG GPAGLTAALY GARGGLNTIL LEMGAPGGQA GQTDRIENYP GFPDGITGID 70 80 90 100 110 120 LAMKFAEQAQ RFGARLEMTT VREVDFSGAN KKVITSNGEY EARAVIIASG AHPRPLGVPG 130 140 150 160 170 180 EAELRGRGVS YCATCDGAFF RDKKVAVVGG GDSAVEEALF LTRFASQVTI IHRRDALRAT 190 200 210 220 230 240 RVIQDRARDN PKISFQWNTV VNAIQGKDKV SSLQLKDVRT GALREEPFDG VFIFIGLEPN 250 260 270 280 290 300 TDFLGGALTL DPDGYIVTRE DLATSIPGVF AAGDVRAKNF RQVSTAVGDG AVAAMAAERY LANL

References

[1]

"The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum)." Pierce E., Xie G., Barabote R.D., Saunders E., Han C.S., Detter J.C., Richardson P., Brettin T.S., Das A., Ljungdahl L.G., Ragsdale S.W. Environ. Microbiol. 10:2550-2573(2008) [PubMed: 18631365] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39073.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000232 Genomic DNA. Translation: ABC20702.1.
RefSeq	YP_431245.1. NC_007644.1.
3D structure databases
ProteinModelPortal	Q2RFT7.
SMR	Q2RFT7. Positions 2-303.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2RFT7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3832171.
GenomeReviews	Gene locus Moth_2420 in contig CP000232_GR.
KEGG	mta:Moth_2420.
NMPDR	fig|264732.9.peg.2453.
PATRIC	22642346. VBIMooThe6753_2637.
Phylogenomic databases
eggNOG	COG0492.
HOGENOM	HBG669726.
OMA	RMETKIP.
PhylomeDB	Q2RFT7.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. [Graphical view]
KO	K00384.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2RFT7_MOOTA

Accession

Primary (citable) accession number: Q2RFT7

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)